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Q3ATC0 (UPPP_CHLCH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Cag_0482
OrganismChlorobium chlorochromatii (strain CaD3) [Complete proteome] [HAMAP]
Taxonomic identifier340177 [NCBI]
Taxonomic lineageBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 282282Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000227613

Regions

Transmembrane39 – 5921Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane115 – 13521Helical; Potential
Transmembrane153 – 17321Helical; Potential
Transmembrane196 – 21621Helical; Potential
Transmembrane230 – 25021Helical; Potential
Transmembrane260 – 28021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q3ATC0 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 9148B5EE7B772026

FASTA28230,034
        10         20         30         40         50         60 
MSLFEALILG IVQGLTEFLP ISSTAHLRII PALAGWNDPG AAFTAIVQMG TLAAVLIYFR 

        70         80         90        100        110        120 
SDIVCIVKAV VDGLLKGKPL NTPDATMGWM IAAGTIPIVF FGLLFKDAIE TTLRSLYWIS 

       130        140        150        160        170        180 
AALIGLALIL WLTEVRLKQR VAKHLPLKSM EEIGWKEALL IGVAQSIALI PGSSRSGTTI 

       190        200        210        220        230        240 
TGGLLLNLSR EAAARFSFLL SLPSVLAAAL LQLYETRHSL LASPSELTNL LVATIAAGVV 

       250        260        270        280 
GYASIAFLIT YLKEHSTSVF IIYRIVIGVA ILGLIATGAI QP 

« Hide

References

[1]"Complete sequence of Chlorobium chlorochromatii CaD3."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CaD3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000108 Genomic DNA. Translation: ABB27755.1.
RefSeqYP_378798.1. NC_007514.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING340177.Cag_0482.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB27755; ABB27755; Cag_0482.
GeneID3748207.
KEGGcch:Cag_0482.
PATRIC21368561. VBIChlChl46571_0504.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.
ProtClustDBPRK12554.

Enzyme and pathway databases

BioCycCCHL340177:GHBW-493-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_CHLCH
AccessionPrimary (citable) accession number: Q3ATC0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 22, 2005
Last modified: February 19, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families