Q3ASI5 (ARGB_CHLCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetylglutamate kinase
EC=2.7.2.8

Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK

Gene names

Name:	argB
Ordered Locus Names:	Cag_0774

Organism

Chlorobium chlorochromatii (strain CaD3) [Complete proteome] [HAMAP]

Taxonomic identifier

340177 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00082_B.
Sequence similarities	Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetylglutamate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 286	286	Acetylglutamate kinase HAMAP MF_00082_B		PRO_0000264692
Regions
	Region	69 – 70	2	Substrate binding By similarity
Sites
	Binding site	91	1	Substrate By similarity
	Binding site	185	1	Substrate By similarity
	Site	34	1	Transition state stabilizer By similarity
	Site	244	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3ASI5 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 0E1645E55FF571DB	FASTA	286	30,464
	10 20 30 40 50 60 MSSERKAPHA AIGQVLIEAL PYIRQFEGKT FVIKYGGAAM KDDTLKNMFA QNVTLLRKVG 70 80 90 100 110 120 IRIVLVHGGG DAITRTAEKL GLQSRFVQGR RVTDKEMISV IQMTLAGKVN QDIVQLISEH 130 140 150 160 170 180 GGKAVGVSGL DADTIKAHPH PNAEQLGLVG EVEQINTDYI DLLSQAGLIP VIAPVGFDCD 190 200 210 220 230 240 GNLYNINADD AASSISIALK AEKLIYVSDV AGIQVGDKIL KTISKAEAAD LIERGIISGG 250 260 270 280 MIPKVVSAFN TMDGGVGKVH LIDGKSTHSL LLEIFTHEGV GTQFIN

References

[1]

"Complete sequence of Chlorobium chlorochromatii CaD3." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CaD3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000108 Genomic DNA. Translation: ABB28040.1.
RefSeq	YP_379083.1. NC_007514.1.
3D structure databases
HSSP	HSSP built from PDB template 2BUF based on UniProtKB Q9HTN2.
ProteinModelPortal	Q3ASI5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3ASI5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3747618.
GenomeReviews	Gene locus Cag_0774 in contig CP000108_GR.
KEGG	cch:Cag_0774.
PATRIC	21369163. VBIChlChl46571_0799.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0548.
HOGENOM	HBG497643.
OMA	GGNAMID.
PhylomeDB	Q3ASI5.
ProtClustDB	PRK00942.
Enzyme and pathway databases
BioCyc	CCHL340177:CAG_0774-MONOMER.
Family and domain databases
HAMAP	MF_00082_B. ArgB_B. [Tree]
InterPro	IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KO	K00930.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000728. NAGK. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00761. ArgB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGB_CHLCH

Accession

Primary (citable) accession number: Q3ASI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program