Q3ARK5 (Q3ARK5_CHLCH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862
EC=1.5.1.20 RuleBase RU003862

Gene names

Ordered Locus Names:

Cag_1108

Organism

Chlorobium chlorochromatii (strain CaD3) [Complete proteome] [HAMAP]

Taxonomic identifier

340177 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862
Cofactor	FAD By similarity. RuleBase RU003862
Sequence similarities	Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Ontologies

Keywords
Ligand	FAD RuleBase RU003862 Flavoprotein RuleBase RU003862
Molecular function	Oxidoreductase RuleBase RU003862
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	methionine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	methylenetetrahydrofolate reductase (NADPH) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3ARK5 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 37D80A2FCACD7352	FASTA	289	32,022
	10 20 30 40 50 60 MLVKEILSAA NNPVFSFEFF PPKKDEEWDT LFKTIAALSP LHPSYVSVTY GAGGSTRSRT 70 80 90 100 110 120 HNLVTRIQQE TGLTVVSHLT CISSEESDTE AILRNYQENG INNVLALRGD KPTGVATLQE 130 140 150 160 170 180 AIKDFPHAID LVRFIKRNFP DFGVGVAGFP EGHPETPNRM QEIEYLKAKV DAGADYIVTQ 190 200 210 220 230 240 LFFDNRDYFD FVERCQLAGI TVPVIPGIMP IATKKGMIRM SELALGSRIP APLIKQVLAA 250 260 270 280 ENDSDVAAIG IEWATAQVQE LINQHIRGIH FYTLNMADAT LKIFRNLSA

References

[1]

"Complete sequence of Chlorobium chlorochromatii CaD3." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CaD3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000108 Genomic DNA. Translation: ABB28370.1.
RefSeq	YP_379413.1. NC_007514.1.
3D structure databases
ProteinModelPortal	Q3ARK5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3ARK5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3748326.
GenomeReviews	Gene locus Cag_1108 in contig CP000108_GR.
KEGG	cch:Cag_1108.
PATRIC	21369873. VBIChlChl46571_1150.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0685.
HOGENOM	HBG649727.
OMA	ITQMFFD.
PhylomeDB	Q3ARK5.
ProtClustDB	CLSK637732.
Family and domain databases
InterPro	IPR003171. Mehydrof_redctse. IPR004620. MTHF_reductase_bac. [Graphical view]
KO	K00297.
Pfam	PF02219. MTHFR. 1 hit. [Graphical view]
TIGRFAMs	TIGR00676. Fadh2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3ARK5_CHLCH

Accession

Primary (citable) accession number: Q3ARK5

Entry history

Integrated into UniProtKB/TrEMBL:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)