Q3AQL3 (KGUA_CHLCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Guanylate kinase
EC=2.7.4.8

Alternative name(s):
GMP kinase

Gene names

Name:	gmk
Ordered Locus Names:	Cag_1456

Organism

Chlorobium chlorochromatii (strain CaD3) [Complete proteome] [HAMAP]

Taxonomic identifier

340177 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP MF_00328
Catalytic activity	ATP + GMP = ADP + GDP. HAMAP MF_00328
Subcellular location	Cytoplasm By similarity HAMAP MF_00328.
Sequence similarities	Belongs to the guanylate kinase family. Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Guanylate kinase HAMAP MF_00328		PRO_0000266305
Regions
	Domain	7 – 186	180	Guanylate kinase-like
	Nucleotide binding	14 – 21	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3AQL3 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 97C14C7039F8FECB	FASTA	190	20,968
	10 20 30 40 50 60 MAVEPSGKLI VFSAPSGAGK TTIATMVLQR IANLSFSVSA TTRKQREGEQ DGVNYYFLDK 70 80 90 100 110 120 ATFEKKIEQG GFIEHEFFFG NYYGTLLDAT ESVLASGKNL LLDVDVKGAL NVRKLFGERS 130 140 150 160 170 180 LLIFIQPPSM EVLIERLQGR GSEDDAALQE RLERARFEMS FADQFDTIIV NNNLTAAVDD 190 VEAAIVNFIG

References

[1]

"Complete sequence of Chlorobium chlorochromatii CaD3." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CaD3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000108 Genomic DNA. Translation: ABB28712.1.
RefSeq	YP_379755.1. NC_007514.1.
3D structure databases
HSSP	HSSP built from PDB template 2AN9 based on UniProtKB P60546.
ProteinModelPortal	Q3AQL3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3AQL3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3746654.
GenomeReviews	Gene locus Cag_1456 in contig CP000108_GR.
KEGG	cch:Cag_1456.
PATRIC	21370619. VBIChlChl46571_1512.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0194.
HOGENOM	HBG671982.
OMA	EWAEFAG.
PhylomeDB	Q3AQL3.
ProtClustDB	PRK00300.
Enzyme and pathway databases
BioCyc	CCHL340177:CAG_1456-MONOMER.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase. [Tree]
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. [Graphical view]
KO	K00942.
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR03263. Guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KGUA_CHLCH

Accession

Primary (citable) accession number: Q3AQL3

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program