Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q3APY5

- SYL_CHLCH

UniProt

Q3APY5 - SYL_CHLCH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Chlorobium chlorochromatii (strain CaD3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei579 – 5791ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCCHL340177:GHBW-1704-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:Cag_1688
OrganismiChlorobium chlorochromatii (strain CaD3)
Taxonomic identifieri340177 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
ProteomesiUP000002708: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 805805Leucine--tRNA ligasePRO_1000009320Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi340177.Cag_1688.

Structurei

3D structure databases

ProteinModelPortaliQ3APY5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi40 – 5112"HIGH" regionAdd
BLAST
Motifi576 – 5805"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiERYWMNV.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3APY5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKYDFTSIEK KWQTRWQAEA TFATGTDHSK PKYYVLDMFP YPSGSGLHVG
60 70 80 90 100
HLEGYTASDI IARYKRSSGY NVLHPMGWDA FGLPAEQFAI KTGTHPRITT
110 120 130 140 150
EANVKNFKGT LQAMGFSYDW EREINTTDSG YFKWTQWIFL QLYDRGLAYM
160 170 180 190 200
SEVDVNWCEE LKTVLANEEV DEKLADGYTV VRRPLRQWVL KITAYAERLL
210 220 230 240 250
ADLEELDWPE NVKQMQRNWI GRSEGVEIDF ELRCHRTTLK AYTTRPDTLF
260 270 280 290 300
GATYLVIAPE HPMAEKLATA PQLLVVKEYI TKAKLKSDLE RTGLQKEKSG
310 320 330 340 350
VFTGSYAINP ATGQPLPIWI SDFVLISYGT GAIMSVPAHD SRDWAFAKQY
360 370 380 390 400
NLPIIEVIKS PHDVQEAVFE EKNSTCVNSA NDEISLNGLD FATAFERMAT
410 420 430 440 450
WLESKKVGKR KVNYKLRDWI FSRQRYWGEP IPIKHYEDGT IRPETNLPLE
460 470 480 490 500
LPAVEAYHPT STGESPLANI TEWLIGNDEH GAFRRETNTM PQWAGSCWYY
510 520 530 540 550
LRFIDPHNHA QVVDGNNERY WMNVDLYIGG AEHAVLHLLY SRFWHKVLYD
560 570 580 590 600
LGVVSTKEPF QKLFNQGMIL GEDNEKMSKS RGNVIPADHV LQRYGADAVR
610 620 630 640 650
LYEMFLGPLE QVKPWNTNGI EGISRFLGKV WRFVYPEHSE AATQPSNEPL
660 670 680 690 700
PDELLRRMHK TIKKVGDDTS SLKFNTAIAE MMVFVNELTK TGCNNREAIE
710 720 730 740 750
TLLKLLAPYA PHMTEELWEA LGHTNSISHE PFPTFNPALV EENMAIIAVQ
760 770 780 790 800
VNGKLRGTFT VPAKSPKEML LEEARKVESV AKFLEGKTIV KEIVVPDKLV

NFAVK
Length:805
Mass (Da):92,007
Last modified:November 22, 2005 - v1
Checksum:iA0C78B83732AF54C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000108 Genomic DNA. Translation: ABB28940.1.
RefSeqiYP_379983.1. NC_007514.1.

Genome annotation databases

EnsemblBacteriaiABB28940; ABB28940; Cag_1688.
GeneIDi3746378.
KEGGicch:Cag_1688.
PATRICi21371119. VBIChlChl46571_1754.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000108 Genomic DNA. Translation: ABB28940.1 .
RefSeqi YP_379983.1. NC_007514.1.

3D structure databases

ProteinModelPortali Q3APY5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 340177.Cag_1688.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABB28940 ; ABB28940 ; Cag_1688 .
GeneIDi 3746378.
KEGGi cch:Cag_1688.
PATRICi 21371119. VBIChlChl46571_1754.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi ERYWMNV.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci CCHL340177:GHBW-1704-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Chlorobium chlorochromatii CaD3."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CaD3.

Entry informationi

Entry nameiSYL_CHLCH
AccessioniPrimary (citable) accession number: Q3APY5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 22, 2005
Last modified: October 29, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3