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Q3APP1 (Q3APP1_CHLCH) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotate dehydrogenase HAMAP MF_00224
Short name=DHOD HAMAP MF_00224
Short name=DHODase HAMAP MF_00224
Short name=DHOdehase HAMAP MF_00224
EC=1.3.-.- HAMAP MF_00224
Gene names
Name:pyrD HAMAP MF_00224
Ordered Locus Names:Cag_1783
OrganismChlorobium chlorochromatii (strain CaD3) [Complete proteome] [HAMAP]
Taxonomic identifier340177 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of dihydroorotate to orotate By similarity. HAMAP MF_00224

Catalytic activity

(S)-dihydroorotate + acceptor = orotate + reduced acceptor. HAMAP MF_00224

Cofactor

Binds 1 FMN per subunit By similarity. HAMAP MF_00224 SAAS SAAS012135

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway. HAMAP MF_00224

Subcellular location

Cytoplasm By similarity HAMAP MF_00224.

Sequence similarities

Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. HAMAP MF_00224

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1391Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

Sequence LengthMass (Da)Tools
Q3APP1 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 5949F0C43C8FE67A

FASTA31333,053
        10         20         30         40         50         60 
MTLQTSSPTT ATALSLGRGL ELTSPVLLAS GTVSYGEEIS QLCNLSRIGG IVTKAISLEP 

        70         80         90        100        110        120 
RAGNPPQRIA ETPSGMINAI GLANVGVERF IADKVPFLRQ LNTAVIVNIA GRSIDDYCEV 

       130        140        150        160        170        180 
VSRLDGVEGL DGYEINLSCP NVKGECMIMG VSSEMTYEIV SALRSITPRH LMIKLTPNVT 

       190        200        210        220        230        240 
SISTIALAAE KAGADSLSLI NTVVGMAVNY KTRKPLLKNV TGGLSGPAIK PIALAKVWEV 

       250        260        270        280        290        300 
YQAVSIPIVG MGGIASFEDA MEFLLVGARA IQIGTMNFVY PDISEKIAVA LEAHFAAPNA 

       310 
MPLRDYCGSL QVE

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References

[1]"Complete sequence of Chlorobium chlorochromatii CaD3."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CaD3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000108 Genomic DNA. Translation: ABB29034.1.
RefSeqYP_380077.1. NC_007514.1.

3D structure databases

ProteinModelPortalQ3APP1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3APP1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3747203.
GenomeReviewsGene locus Cag_1783 in contig CP000108_GR.
KEGGcch:Cag_1783.
PATRIC21371330. VBIChlChl46571_1859.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0167.
HOGENOMHBG472415.
OMAVALRMVW.
PhylomeDBQ3APP1.
ProtClustDBCLSK637846.

Family and domain databases

HAMAPMF_00224. DHO_dh_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR005720. Dihydroorotate_DH.
IPR024920. Dihydroorotate_DH_1.
IPR012135. Dihydroorotate_DH_1_2.
IPR001295. Dihydroorotate_DH_CS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00226.
PfamPF01180. DHO_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsTIGR01037. PyrD_sub1_fam. 1 hit.
PROSITEPS00912. DHODEHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ3APP1_CHLCH
AccessionPrimary (citable) accession number: Q3APP1
Entry history
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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