Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q3AMJ2

- PUR5_SYNSC

UniProt

Q3AMJ2 - PUR5_SYNSC

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Synechococcus sp. (strain CC9605)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 2 (31 Oct 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Purine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSSP110662:GJ7R-428-MONOMER.
    UniPathwayiUPA00074; UER00129.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
    Alternative name(s):
    AIR synthaseUniRule annotation
    AIRSUniRule annotation
    Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
    Gene namesi
    Name:purMUniRule annotation
    Ordered Locus Names:Syncc9605_0414
    OrganismiSynechococcus sp. (strain CC9605)
    Taxonomic identifieri110662 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
    ProteomesiUP000002711: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 345345Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000258422Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi110662.Syncc9605_0414.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3AMJ2.
    SMRiQ3AMJ2. Positions 1-340.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIR synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0150.
    HOGENOMiHOG000229090.
    KOiK01933.
    OrthoDBiEOG61CM1V.

    Family and domain databases

    Gene3Di3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPiMF_00741_B. AIRS_B.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsiTIGR00878. purM. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3AMJ2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDYKSAGVDV EAGRAFVQRI KASVEATHRP EVIGGLGGFG GLMSLPAGMR    50
    KPLLVSGTDG VGTKLELAQE HGSHHGVGID LVAMCVNDVI TSGAAPLFFL 100
    DYMATGALAP SAMAEVVEGI ADGCRQSGCA LLGGETAEMP GFYPQGRYDI 150
    AGFCVAVVEE DELIDGQRIQ PGDSVIGVAS SGVHSNGFSL VRKVLEKANA 200
    DANTVYGDNQ RPLIGDLLAP TTLYADLVQH LMQSGCELHG MAHITGGGLP 250
    ENLPRCLPEG CSARIDASSW TRPTLFRWLQ EAGNIPERDL WHTFNLGIGF 300
    CLVVPARSED AVIEHCRGKN HQAWLIGNVT SNTPGNAAVL EGVPA 345
    Length:345
    Mass (Da):36,254
    Last modified:October 31, 2006 - v2
    Checksum:i902811338F574327
    GO

    Sequence cautioni

    The sequence ABB34190.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000110 Genomic DNA. Translation: ABB34190.1. Different initiation.
    RefSeqiWP_011363427.1. NC_007516.1.
    YP_380745.1. NC_007516.1.

    Genome annotation databases

    EnsemblBacteriaiABB34190; ABB34190; Syncc9605_0414.
    GeneIDi3736511.
    KEGGisyd:Syncc9605_0414.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000110 Genomic DNA. Translation: ABB34190.1 . Different initiation.
    RefSeqi WP_011363427.1. NC_007516.1.
    YP_380745.1. NC_007516.1.

    3D structure databases

    ProteinModelPortali Q3AMJ2.
    SMRi Q3AMJ2. Positions 1-340.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 110662.Syncc9605_0414.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB34190 ; ABB34190 ; Syncc9605_0414 .
    GeneIDi 3736511.
    KEGGi syd:Syncc9605_0414.

    Phylogenomic databases

    eggNOGi COG0150.
    HOGENOMi HOG000229090.
    KOi K01933.
    OrthoDBi EOG61CM1V.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00129 .
    BioCyci SSP110662:GJ7R-428-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPi MF_00741_B. AIRS_B.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsi TIGR00878. purM. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Synechococcus sp. CC9605."
      US DOE Joint Genome Institute
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CC9605.

    Entry informationi

    Entry nameiPUR5_SYNSC
    AccessioniPrimary (citable) accession number: Q3AMJ2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: October 31, 2006
    Last modified: October 1, 2014
    This is version 63 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3