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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Synechococcus sp. (strain CC9605)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciSSP110662:GJ7R-825-MONOMER.
UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:Syncc9605_0797
OrganismiSynechococcus sp. (strain CC9605)
Taxonomic identifieri110662 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
Proteomesi
  • UP000002711 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 502502Probable malate:quinone oxidoreductasePRO_0000325514Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi110662.Syncc9605_0797.

Structurei

3D structure databases

ProteinModelPortaliQ3ALG7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OrthoDBiPOG091H0B7C.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3ALG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQHDGSFNPE ARFDAVLVGA GIMSATLAAL LHELDTQLRI LLVERLEAPA
60 70 80 90 100
LESSAAVNNA GTGHAANCEL NYTPIQADGT VATAKAVAIN TSFERSLEFW
110 120 130 140 150
SSLQERGDLD TSSFLHQAAH ISAVWTPENI AFLRQRFSQL KELPAFARMR
160 170 180 190 200
WSEDQSELTE WMPLVMAGRD LKQPVAATRI DRGTDVDFGS LTRAYLMPLQ
210 220 230 240 250
QSGALSVEYG TQVHDLKRLR HSDMTEADWR VVLKGPSGKK EVRAPFVFLG
260 270 280 290 300
AGGGALPLLQ RSGIPEAADF AGFPVSGLWL VCGDAQLADR QRAKVYGKAA
310 320 330 340 350
VGAPPMSVPH LDTRWVDGKR SLLFGPFAGF SSKFLKQGSL LDLPASVRAT
360 370 380 390 400
NLLPMLQVGA TNFELVQYLI NQLRQSPTQR HEALQQFMPT ARAEDWTLSV
410 420 430 440 450
AGQRVQIIKR SKQGGRLQLG TEVVASGDGS LAALLGASPG ASTAVTIMLE
460 470 480 490 500
VLERCFKQRL DSDAWQQRLQ ALLPSIHEDP HQDPQVLNRM RERSDALLGL

TA
Length:502
Mass (Da):54,791
Last modified:March 18, 2008 - v2
Checksum:iDE2E8AE8A3628673
GO

Sequence cautioni

The sequence ABB34565 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000110 Genomic DNA. Translation: ABB34565.1. Different initiation.
RefSeqiWP_041434464.1. NC_007516.1.

Genome annotation databases

EnsemblBacteriaiABB34565; ABB34565; Syncc9605_0797.
KEGGisyd:Syncc9605_0797.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000110 Genomic DNA. Translation: ABB34565.1. Different initiation.
RefSeqiWP_041434464.1. NC_007516.1.

3D structure databases

ProteinModelPortaliQ3ALG7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi110662.Syncc9605_0797.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB34565; ABB34565; Syncc9605_0797.
KEGGisyd:Syncc9605_0797.

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OrthoDBiPOG091H0B7C.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.
BioCyciSSP110662:GJ7R-825-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMQO_SYNSC
AccessioniPrimary (citable) accession number: Q3ALG7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: September 7, 2016
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.