Q3ALF2 (SYGA_SYNSC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	Syncc9605_0812

Organism

Synechococcus sp. (strain CC9605) [Complete proteome] [HAMAP]

Taxonomic identifier

110662 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 296	296	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000047520

Sequences

	Sequence		Length	Mass (Da)
	Q3ALF2 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: B3888D8F4C305732	FASTA	296	33,561
	10 20 30 40 50 60 MYFQDIISTL NRFWADQGCL LLQPYDTEKG AGTMSPHTVL RAIGPEPWAV AYPEPCRRPT 70 80 90 100 110 120 DGRYGDNPNR AQHYFQYQVL IKPSPDGIQE TYLASLEALG IKAADHDIRF VEDNWESPTL 130 140 150 160 170 180 GAWGVGWEVW LDGMEVTQFT YFQQCGGIDC KPVSIEITYG LERLAMYLQD VESIWDLSWN 190 200 210 220 230 240 SERSYGEIWL PFEKGQCHFN FEASNPERLK QLFAIYEAEA ADLIEKQLPA PALDFVLKCS 250 260 270 280 290 HTFNLLEARG VISVTERTAT IVRIRNLARK VAEAWLAERE ALGFPLLKGG TLETAA

References

[1]

"Complete sequence of Synechococcus sp. CC9605." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CC9605.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000110 Genomic DNA. Translation: ABB34580.1.
RefSeq	YP_381135.1. NC_007516.1.
3D structure databases
HSSP	HSSP built from PDB template 1J5W based on UniProtKB Q9WY59.
ProteinModelPortal	Q3ALF2.
SMR	Q3ALF2. Positions 1-276.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3ALF2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3735374.
GenomeReviews	Gene locus Syncc9605_0812 in contig CP000110_GR.
KEGG	syd:Syncc9605_0812.
NMPDR	fig|110662.3.peg.326.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0752.
HOGENOM	HBG285316.
OMA	CRRPTDG.
PhylomeDB	Q3ALF2.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	SSP1131:SYNCC9605_0812-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_SYNSC

Accession

Primary (citable) accession number: Q3ALF2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program