Q3AKV6 (GLGB_SYNSC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
1,4-alpha-glucan branching enzyme GlgB
EC=2.4.1.18

Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE

Gene names

Name:	glgB
Ordered Locus Names:	Syncc9605_1018

Organism

Synechococcus sp. (strain CC9605) [Complete proteome] [HAMAP]

Taxonomic identifier

110662 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	765 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP MF_00685
Catalytic activity	Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP MF_00685
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00685
Subunit structure	Monomer By similarity. HAMAP MF_00685
Sequence similarities	Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glycogen biosynthesis Glycogen metabolism
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	1,4-alpha-glucan branching enzyme activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro hydrolase activity, hydrolyzing O-glycosyl compounds Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 765	765	1,4-alpha-glucan branching enzyme GlgB HAMAP MF_00685		PRO_0000260706
Sites
	Active site	431	1	Nucleophile By similarity
	Active site	484	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3AKV6 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 39173F2F383AB68B	FASTA	765	88,028
	10 20 30 40 50 60 MGVAAVLDWL VQDGERLASC RHDHPFAVLG PQASDQGWTV RMWMPEAQSV SLLQAGEEIA 70 80 90 100 110 120 MTTPNHPWVF EAQVSQDPGC HYRVKVERGG IVHEQHDPWA FRGEWMGEMD RHLFAEGNHH 130 140 150 160 170 180 HIWQKMGAHL TERDGITGVM FCLWAPNALS VSVIGDLNSW DGRHHPMQQR VGGIWELFVP 190 200 210 220 230 240 GLEEGHLYKY EIRTQDGHCY QKADPYGFQH EVRPDNSSVV ARLNGFQWSD QTWMQKRDSS 250 260 270 280 290 300 NALDQPISVY EMHLGSWIHA SADEPWIQPD GTPRPPVPAA DMKPGARLLT YAELADRLIP 310 320 330 340 350 360 YVKDRGFTHI EVMPITEHPF DGSWGYQVTG WYAPTSRYGT PDEFRAFVDR CHAEGIGVII 370 380 390 400 410 420 DWVPGHFPKD AHGLAFFDGA HLYEHSDPRI GEHKEWGTLI FNYSRNEVRN FLVANLIFWF 430 440 450 460 470 480 EQFHIDGIRV DAVASMLYRD YLRPDGEWLP NESGGRENTE AVRFLQQANH VLFQHFPGAL 490 500 510 520 530 540 SIAEESTTWP MVTQPTDSGG LGFNLKWNMG WMHDMLDYFE LDPWFRQFHQ NNITFSIWYT 550 560 570 580 590 600 YTENFMLALS HDEVVHGKSH LMHKMPGDDW QKYANTRALL SYMWTHPGKK TIFMGMEFGQ 610 620 630 640 650 660 RAEWNVWGDL QWDLLNYEPH KGIQRLVDDL NVLYKAEPAL WRDDFDQFGF QWIDCNDNRH 670 680 690 700 710 720 SVISFMRRES ASGTWLVVVA NFTPQSHSHY RVGVPLSGFY EEIFNSDAAK YGGSNLGNMG 730 740 750 760 GKPTDEWGIH GYENSLDLCL PPLSLMVFKH DPKRSLNSSE PDNIV

References

[1]

"Complete sequence of Synechococcus sp. CC9605." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CC9605.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000110 Genomic DNA. Translation: ABB34776.1.
RefSeq	YP_381331.1. NC_007516.1.
3D structure databases
ProteinModelPortal	Q3AKV6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3AKV6.
Protein family/group databases
CAZy	CBM48. Carbohydrate-Binding Module Family 48. GH13. Glycoside Hydrolase Family 13.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3735265.
GenomeReviews	Gene locus Syncc9605_1018 in contig CP000110_GR.
KEGG	syd:Syncc9605_1018.
NMPDR	fig|110662.3.peg.1271.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0296.
HOGENOM	HBG287139.
OMA	DGTCLYE.
PhylomeDB	Q3AKV6.
ProtClustDB	PRK05402.
Enzyme and pathway databases
BioCyc	SSP1131:SYNCC9605_1018-MONOMER.
Family and domain databases
HAMAP	MF_00685. GlgB. [Tree]
InterPro	IPR006407. 1-4-A-glucan_branch_enz. IPR006048. A-amylase_b_C. IPR015902. Alpha_amylase. IPR013780. Glyco_hydro_13_b. IPR006047. Glyco_hydro_13_cat_dom. IPR004193. Glyco_hydro_13_N. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. [Graphical view]
Gene3D	G3DSA:2.60.40.1180. Glyco_hydro_13_b. 1 hit. G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit. G3DSA:2.60.40.10. Ig-like_fold. 2 hits.
KO	K00700.
PANTHER	PTHR10357. Alpha_amylase. 1 hit. PTHR10357:SF13. PTHR10357:SF13. 1 hit.
Pfam	PF00128. Alpha-amylase. 1 hit. PF02806. Alpha-amylase_C. 1 hit. PF02922. CBM_48. 1 hit. [Graphical view]
PIRSF	PIRSF000463. GlgB. 1 hit.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit. SSF81296. Ig_E-set. 1 hit.
TIGRFAMs	TIGR01515. Branching_enzym. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGB_SYNSC

Accession

Primary (citable) accession number: Q3AKV6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program