Q3AKI8 (Q3AKI8_SYNSC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123

Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123

Gene names

Name:	acsA HAMAP MF_01123
Ordered Locus Names:	Syncc9605_1139

Organism

Synechococcus sp. (strain CC9605) [Complete proteome] [HAMAP]

Taxonomic identifier

110662 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	657 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123
Post-translational modification	Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123
Sequence similarities	Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Ontologies

Keywords
Ligand	ATP-binding HAMAP MF_01123 Nucleotide-binding
Molecular function	Ligase HAMAP MF_01123 EMBL ABB34894.1
PTM	Acetylation HAMAP MF_01123
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	AMP binding Inferred from electronic annotation. Source: InterPro ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate-CoA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	532	1	By similarity HAMAP MF_01123
Amino acid modifications
	Modified residue	624	1	N6-acetyllysine By similarity HAMAP MF_01123

Sequences

	Sequence		Length	Mass (Da)
	Q3AKI8 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 4108D3F1C3B55CF9	FASTA	657	71,665
	10 20 30 40 50 60 MTDANTTIES VLQEQRVFEP PADTAAKARI GSLEAYRAMA DAAKADPDAF WGEAARRELH 70 80 90 100 110 120 WFEPFHTVLD WSNPPFARWF EGGTTNLSYN CLDRHLDGPT AQKTALIWEG EPGDVRRFTY 130 140 150 160 170 180 QELHAEVCKA ANGLKAMGIG KGHLVALYMP MVPEAAIAML ACARIGAPHS VVFGGFSAEA 190 200 210 220 230 240 LRDRLNDGEV KAVITADGGF RKDKPVSLKP AVDAALANGA CPSVMGVLVV QRTKQDVEMV 250 260 270 280 290 300 SGRDQWWHDL VEGQSADCPA EPMASEDRLF VLYTSGSTGK PKGVVHTTAG YNLWAHLTFQ 310 320 330 340 350 360 WIFDIQYEDV FWCTADVGWI TGHSYIVYGP LSNGATTVMY EGAPRPSKPG AFWELIQKHG 370 380 390 400 410 420 ITIFYTAPTA IRAFMKSGRS VPDQFDMSSL RLLGTVGEPI NPEAWMWYRD VIGGNRCPIV 430 440 450 460 470 480 DTWWQTETGG VMISPLPGAT PTKPGSATLP LPGIQADVID AEGNSCGADE GGYLAVRAPW 490 500 510 520 530 540 PGMMRTVHGN PQRFRESYWE HIRPADGSYL YFAGDGARRD ADGYFWVMGR VDDVINVSGH 550 560 570 580 590 600 RLGTMEIESA LVSHPAVAEA AVVGRPDDLK GEGIVAFVTL EACREGDDAL VKELRAHVGT 610 620 630 640 650 EIGPIARPDE IRCSDALPKT RSGKIMRRIL RALAAGQEVS GDTSTLEDRS VLDRLRA

References

[1]

"Complete sequence of Synechococcus sp. CC9605." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CC9605.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000110 Genomic DNA. Translation: ABB34894.1.
RefSeq	YP_381449.1. NC_007516.1.
3D structure databases
ProteinModelPortal	Q3AKI8.
SMR	Q3AKI8. Positions 20-656.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3AKI8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3735904.
GenomeReviews	Gene locus Syncc9605_1139 in contig CP000110_GR.
KEGG	syd:Syncc9605_1139.
NMPDR	fig|110662.3.peg.108.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0365.
HOGENOM	HBG547964.
OMA	VISVSGH.
PhylomeDB	Q3AKI8.
ProtClustDB	CLSK919509.
Enzyme and pathway databases
BioCyc	SSP1131:SYNCC9605_1139-MONOMER.
Family and domain databases
HAMAP	MF_01123. Ac_CoA_synth. [Tree]
InterPro	IPR011904. Ac_CoA_lig. IPR024597. Acyl-CoA_synth_DUF3448. IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. [Graphical view]
KO	K01895.
PANTHER	PTHR24095:SF42. PTHR24095:SF42. 1 hit.
Pfam	PF00501. AMP-binding. 1 hit. PF11930. DUF3448. 1 hit. [Graphical view]
TIGRFAMs	TIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q3AKI8_SYNSC

Accession

Primary (citable) accession number: Q3AKI8

Entry history

Integrated into UniProtKB/TrEMBL:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)