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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit A

Gene

gatA

Organism
Synechococcus sp. (strain CC9605)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei79Charge relay systemUniRule annotation1
Active sitei154Charge relay systemUniRule annotation1
Active sitei178Acyl-ester intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSP110662:G1G50-1202-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotation (EC:6.3.5.7UniRule annotation)
Short name:
Glu-ADT subunit AUniRule annotation
Gene namesi
Name:gatAUniRule annotation
Ordered Locus Names:Syncc9605_1157
OrganismiSynechococcus sp. (strain CC9605)
Taxonomic identifieri110662 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000002711 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002411691 – 491Glutamyl-tRNA(Gln) amidotransferase subunit AAdd BLAST491

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Protein-protein interaction databases

STRINGi110662.Syncc9605_1157

Structurei

3D structure databases

ProteinModelPortaliQ3AKH0
SMRiQ3AKH0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amidase family. GatA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3P Bacteria
COG0154 LUCA
HOGENOMiHOG000116699
KOiK02433
OMAiPITQNVE
OrthoDBiPOG091H00O9

Family and domain databases

Gene3Di3.90.1300.10, 1 hit
HAMAPiMF_00120 GatA, 1 hit
InterProiView protein in InterPro
IPR000120 Amidase
IPR020556 Amidase_CS
IPR023631 Amidase_dom
IPR036928 AS_sf
IPR004412 GatA
PANTHERiPTHR11895 PTHR11895, 1 hit
PfamiView protein in Pfam
PF01425 Amidase, 1 hit
SUPFAMiSSF75304 SSF75304, 1 hit
TIGRFAMsiTIGR00132 gatA, 1 hit
PROSITEiView protein in PROSITE
PS00571 AMIDASES, 1 hit

Sequencei

Sequence statusi: Complete.

Q3AKH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRRDMTISA WRQQLQSGEV SSRELVDQHL KRLESSEPSL NAFVEVTADQ
60 70 80 90 100
ARAEASRIDE ARAAGEALGP LAGLPLAIKD NLCTKGVRTT CSSRMLEQFV
110 120 130 140 150
PPYESTVTER LWQAGGVLVG KTNLDEFAMG GSTETSAFGA TQNPWNTAHV
160 170 180 190 200
PGGSSGGSAA AVAAGSCVAS LGSDTGGSIR QPASFCGVVG LKPTYGRVSR
210 220 230 240 250
WGLVAFASSL DQVGPFAGSV ADVAELLQVI AGPDPRDSTC LDAAVPVFSD
260 270 280 290 300
GLSQSIKGLK VGLIKECFDA EGLDPEVKAS VQASAAQLEA LGAELVEVSC
310 320 330 340 350
PRFNDGIATY YVIAPSEASA NLARYDGVKY GFRAEDAESL AAMTARSRAE
360 370 380 390 400
AFGAEVQRRI LIGTYALSAG YVDAYYKKAQ QVRTLIRRDF DAAFKSVDVL
410 420 430 440 450
LTPTAPSTAF KAGAHADDPL AMYLADLLTI PVNLAGLPAI SVPCGFSAAG
460 470 480 490
LPIGMQLIGN VLDEPRLLQV AHQYEQAAQV FASRPEAALV P
Length:491
Mass (Da):51,481
Last modified:November 22, 2005 - v1
Checksum:iFD3AF35B14EE2288
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000110 Genomic DNA Translation: ABB34912.1
RefSeqiWP_011364133.1, NC_007516.1

Genome annotation databases

EnsemblBacteriaiABB34912; ABB34912; Syncc9605_1157
KEGGisyd:Syncc9605_1157

Similar proteinsi

Entry informationi

Entry nameiGATA_SYNSC
AccessioniPrimary (citable) accession number: Q3AKH0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 22, 2005
Last modified: April 25, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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