Q3AK74 (FBSB_SYNSC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase
Short name=FBPase class 2/SBPase
EC=3.1.3.11
EC=3.1.3.37

Gene names

Ordered Locus Names:

Syncc9605_1253

Organism

Synechococcus sp. (strain CC9605) [Complete proteome] [HAMAP]

Taxonomic identifier

110662 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively By similarity.
Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. Sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.
Cofactor	Manganese By similarity.
Pathway	Carbohydrate biosynthesis; Calvin cycle.
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the FBPase class 2 family.

Ontologies

Keywords
Biological process	Calvin cycle Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycerol metabolic process Inferred from electronic annotation. Source: InterPro reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW sedoheptulose-bisphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 334	334	D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase		PRO_0000342728
Regions
	Region	88 – 90	3	Substrate binding By similarity
	Region	164 – 166	3	Substrate binding By similarity
	Region	186 – 188	3	Substrate binding By similarity
Sites
	Metal binding	33	1	Manganese 1 By similarity
	Metal binding	57	1	Manganese 1 By similarity
	Metal binding	85	1	Manganese 2 By similarity
	Metal binding	88	1	Manganese 2 By similarity
	Metal binding	213	1	Manganese 2 By similarity
	Binding site	119	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3AK74 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: BB2C4102553FE7A2	FASTA	334	35,307
	10 20 30 40 50 60 MDQTLIQEIL EIVEQAAIAS ASLSGKGLKD EADALAVDAM RKRMNQIQMQ GRIVIGEGER 70 80 90 100 110 120 DEAPMLYIGE EVGTGTGPGV DFAVDPCEGT NLCAFNQRGS MAVLAASDRG GLFNAPDFYM 130 140 150 160 170 180 KKLAAPPAAK GKVDIRKSAT ENIKILSECL GLPVDELNIV VMDRARHKDL IAEIRGTGAR 190 200 210 220 230 240 IQPISDGDVQ AAIACGFAGT GTHCLMGIGA APEGVISAAA MRALGGHFQG QLVYDPAIAQ 250 260 270 280 290 300 TSEWADMTKE GNLARLAEMG IADPDKVYEA EELACGEHVC FAGSGITDGL LFNGVKFEKD 310 320 330 CTRTSSLVIS NLDNTCRFTN TVHIKEDAQS IALS

References

[1]

"Complete sequence of Synechococcus sp. CC9605." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CC9605.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000110 Genomic DNA. Translation: ABB35008.1.
RefSeq	YP_381563.1. NC_007516.1.
3D structure databases
ProteinModelPortal	Q3AK74.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3AK74.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3736457.
GenomeReviews	Gene locus Syncc9605_1253 in contig CP000110_GR.
KEGG	syd:Syncc9605_1253.
NMPDR	fig|110662.3.peg.222.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1494.
HOGENOM	HBG284837.
OMA	TSEWADM.
PhylomeDB	Q3AK74.
ProtClustDB	PRK09479.
Enzyme and pathway databases
BioCyc	SSP1131:SYNCC9605_1253-MONOMER.
Family and domain databases
InterPro	IPR004464. FBPase_class-2/SBPase. [Graphical view]
KO	K11532.
Pfam	PF03320. FBPase_glpX. 1 hit. [Graphical view]
PIRSF	PIRSF004532. GlpX. 1 hit.
TIGRFAMs	TIGR00330. GlpX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FBSB_SYNSC

Accession

Primary (citable) accession number: Q3AK74

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program