Q3AK18 (ACSF_SYNSC) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 45.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase EC=1.14.13.81 | ||||
| Gene names |
| ||||
| Organism | Synechococcus sp. (strain CC9605) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 110662 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Cyanobacteria › Chroococcales › Synechococcus |
Protein attributes
| Sequence length | 356 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840 |
| Catalytic activity | Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840 |
| Cofactor | Iron By similarity. HAMAP MF_01840 |
| Pathway | Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840 |
| Sequence similarities | Belongs to the AcsF family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Chlorophyll biosynthesis Photosynthesis |
| Ligand | Iron Metal-binding NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | chlorophyll biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW photosynthesisInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity Inferred from electronic annotation. Source: EC transition metal ion bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 356 | 356 | Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840 | PRO_1000070556 | |||
Sequences
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References
| [1] | "Complete sequence of Synechococcus sp. CC9605." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CC9605. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000110 Genomic DNA. Translation: ABB35064.1. |
| RefSeq | YP_381619.1. NC_007516.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q3AK18. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 3735865. |
| GenomeReviews | Gene locus Syncc9605_1310 in contig CP000110_GR. |
| KEGG | syd:Syncc9605_1310. |
| NMPDR | fig|110662.3.peg.278. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | NOG10633. |
| HOGENOM | HBG284843. |
| OMA | HGDFFDA. |
| PhylomeDB | Q3AK18. |
| ProtClustDB | PRK13654. |
Enzyme and pathway databases | |
| BioCyc | SSP1131:SYNCC9605_1310-MONOMER. |
Family and domain databases | |
| HAMAP | MF_01840. AcsF. [Tree] |
| InterPro | IPR008434. AcsF. IPR012347. Ferritin-rel. IPR009078. Ferritin/RR-like. IPR003251. Rubrerythrin. [Graphical view] |
| Gene3D | G3DSA:1.20.1260.10. Ferritin_rel. 1 hit. |
| KO | K04035. |
| Pfam | PF02915. Rubrerythrin. 1 hit. [Graphical view] |
| SUPFAM | SSF47240. Ferritin/RR_like. 1 hit. |
| TIGRFAMs | TIGR02029. AcsF. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ACSF_SYNSC | ||||||||
| Accession | Primary (citable) accession number: Q3AK18 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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