Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q3AI99 (Q3AI99_SYNSC) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DNA gyrase subunit A HAMAP MF_01897
EC=5.99.1.3 HAMAP MF_01897
Gene names
Name:gyrA HAMAP MF_01897
Ordered Locus Names:Syncc9605_1942
OrganismSynechococcus sp. (strain CC9605) [Complete proteome] [HAMAP]
Taxonomic identifier110662 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length865 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. SAAS SAAS006691 HAMAP MF_01897

Catalytic activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA. SAAS SAAS006691 HAMAP MF_01897

Subunit structure

Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01897

Subcellular location

Cytoplasm By similarity SAAS SAAS006691 HAMAP MF_01897.

Sequence similarities

Belongs to the topoisomerase GyrA/ParC subunit family. HAMAP MF_01897

Sequences

Sequence LengthMass (Da)Tools
Q3AI99 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 2C86E144F65967B5

FASTA86594,970
        10         20         30         40         50         60 
MTDSVGPGSG GPGDSDDRII QTDLRNEMSR SYLEYAMSVI VGRALPDARD GLKPVHRRIL 

        70         80         90        100        110        120 
YAMYELGLTS DRPYRKCARV VGEVLGKYHP HGDTAVYDAL VRMAQDFSMS MPLIDGHGNF 

       130        140        150        160        170        180 
GSVDNDPPAA MRYTESRLRA LTTDSLLEDI EAETVDFADN FDGSQQEPTV LPARIPQLLL 

       190        200        210        220        230        240 
NGSAGIAVGM ATNIPPHNLN ELIDGLQALI ANPEITDQEL IQLIPGPDFP TGGQILGREG 

       250        260        270        280        290        300 
IRETYLGGRG SVTMRGVANI ETIEAPGRPD RDAVIITELP YQTNKAALIE RIAELVNDKK 

       310        320        330        340        350        360 
LEGISDIRDE SDRDGMRIVV ELRRDAYPQV VLNNLFKLTP LQSNFSAYML ALVNGEPILL 

       370        380        390        400        410        420 
TLRKMLEVFL DFRVETIERR TRYLLRKAEE RDHILLGLLL ALDQLDPIIA LIRAAPDTAT 

       430        440        450        460        470        480 
ARQQLQDRHG LSDIQADAIL QMQLRRLTAL EADKIRLEHE DLVTKIADYK DILGRRERVF 

       490        500        510        520        530        540 
GIIQSELAQL QERYPTPRRT EILDLGGGLS DIDLIANERS VVLLTETGYL KRMPVSEFEA 

       550        560        570        580        590        600 
TSRGTRGKAG TRSQGEDAVK LFISCNDHDT LVLFSDRGVS YALPAYRVPQ CSRAAKGTPV 

       610        620        630        640        650        660 
VQLLPIPREE AITTLIPVSE FSDDTDLVML TRGGFIKRTR LSAFSNIRSN GLIAINLEEG 

       670        680        690        700        710        720 
DALTWVRLAV PGDSVLIGSK AGMTIHFRLS DEELRPLGRT ARGVRSMNLR DADALVSMDV 

       730        740        750        760        770        780 
LPVELADQVA ASADDEDDAA SEGPWVLVAS ASGLGKRVPV TQFRLQKRAG MGLRAMKFRT 

       790        800        810        820        830        840 
DADELVGLSV LGAGEELLLV SEKGVIVRTS ADAIPQQSRA ATGVRLQKLD KGDRLLKVVL 

       850        860 
VPPEAEDDSA DDTESNDTEA VVQDS

« Hide

References

[1]"Complete sequence of Synechococcus sp. CC9605."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CC9605.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000110 Genomic DNA. Translation: ABB35683.1.
RefSeqYP_382238.1. NC_007516.1.

3D structure databases

ProteinModelPortalQ3AI99.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3AI99.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3736610.
GenomeReviewsGene locus Syncc9605_1942 in contig CP000110_GR.
KEGGsyd:Syncc9605_1942.
NMPDRfig|110662.3.peg.2534.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0188.
HOGENOMHBG635183.
OMATSIPPHR.
PhylomeDBQ3AI99.
ProtClustDBPRK05560.

Enzyme and pathway databases

BioCycSSP1131:SYNCC9605_1942-MONOMER.

Family and domain databases

HAMAPMF_01897. GyrA.
[Tree]
InterProIPR005743. GyrA.
IPR006691. GyrA/parC_pinwhl.
IPR002205. Topo_IIA_A/C.
IPR013758. Topo_IIA_A/C_ab.
IPR013757. Topo_IIA_A_a.
IPR013760. Topo_IIA_cen.
[Graphical view]
Gene3DG3DSA:3.90.199.10. Topo_IIA_A/C_ab. 1 hit.
G3DSA:1.10.268.10. Topo_IIA_A_a. 1 hit.
KOK02469.
PfamPF03989. DNA_gyraseA_C. 6 hits.
PF00521. DNA_topoisoIV. 1 hit.
[Graphical view]
SMARTSM00434. TOP4c. 1 hit.
[Graphical view]
SUPFAMSSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMsTIGR01063. GyrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3AI99_SYNSC
AccessionPrimary (citable) accession number: Q3AI99
Entry history
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info