Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Synechococcus sp. (strain CC9605)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciSSP110662:GJ7R-2114-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:Syncc9605_2067
OrganismiSynechococcus sp. (strain CC9605)
Taxonomic identifieri110662 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
Proteomesi
  • UP000002711 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10971097DNA-directed RNA polymerase subunit betaPRO_0000237316Add
BLAST

Proteomic databases

PRIDEiQ3AHX5.

Interactioni

Subunit structurei

In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi110662.Syncc9605_2067.

Structurei

3D structure databases

ProteinModelPortaliQ3AHX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3AHX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSAIQVAK TATYLPDLVE VQRASFKWFL DQGLIEELES FSPITDYTGK
60 70 80 90 100
LELHFIGSEY RLKRPRHDVE EAKRRDATFA SQMYVTCRLV NKETGEIKEQ
110 120 130 140 150
EVFIGELPLM TERGTFIING AERVIVNQIV RSPGVYFKDE MDKNGRRTYN
160 170 180 190 200
ASVIPNRGAW LKFETDKNDL LHVRVDKTRK INAHVLMRAM GLSDNDVLDK
210 220 230 240 250
LRHPEFYKKS IDAANDEGIS SEDQALLELY KKLRPGEPPS VSGGQQLLQT
260 270 280 290 300
RFFDPKRYDL GRVGRYKINK KLRLTIPDTV RTLTHEDVLS TLDYLINLEL
310 320 330 340 350
DVGGASLDDI DHLGNRRVRS VGELLQNQVR VGLNRLERII KERMTVGETD
360 370 380 390 400
SLTPAQLVNP KPLVAAIKEF FGSSQLSQFM DQTNPLAELT HKRRISALGP
410 420 430 440 450
GGLTRERAGF AVRDIHPSHY GRLCPIETPE GPNAGLINSL ATHARVNEYG
460 470 480 490 500
FIETPFWKVE YGVVLKDGDP IYLSADREDE VRVAPGDVAT EDDGRISADL
510 520 530 540 550
IPVRYRQDFE KVPPEQVDYV ALSPVQVISV ATSLIPFLEH DDANRALMGS
560 570 580 590 600
NMQRQAVPLL RPERALVGTG LETQVARDSG MVPISRVNGT VTYVDANAIV
610 620 630 640 650
VQDEDGNDHT HFLQKYQRSN QDTCLNQRPI VRCGDPVIVG QVMADGSACE
660 670 680 690 700
GGEIALGQNV LIAYMPWEGY NYEDALLVSE RLVTDDLYTS VHIEKYEIEA
710 720 730 740 750
RQTKLGPEEI TREIPNVAEE SLGNLDEMGI IRVGAFVESG DILVGKVTPK
760 770 780 790 800
GESDQPPEEK LLRAIFGEKA RDVRDNSLRV PGTERGRVVD VRIYTREQGD
810 820 830 840 850
ELPPGANMVV RVYVAQRRKI QVGDKMAGRH GNKGIISRIL PREDMPYLPD
860 870 880 890 900
GTPVDIVLNP LGVPSRMNVG QVFELLMGWA ASNLDCRVRI VPFDEMHGAE
910 920 930 940 950
KSQQTVETFL KEAAKQPGKG WVYDPEDPGK LQLRDGRTGL PFDQPVAVGY
960 970 980 990 1000
SHFLKLVHLV DDKIHARSTG PYSLVTQQPL GGKAQQGGQR LGEMEVWALE
1010 1020 1030 1040 1050
AYGAAYTLQE LLTVKSDDMQ GRNEALNAIV KGKPIPRPGT PESFKVLMRE
1060 1070 1080 1090
LQSLGLDIAV YTDEGKEVDL MQDVNPRRST PSRPTYESLG VADYDED
Length:1,097
Mass (Da):122,559
Last modified:November 22, 2005 - v1
Checksum:i365C0EA8A74BB275
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000110 Genomic DNA. Translation: ABB35807.1.
RefSeqiWP_011365016.1. NC_007516.1.

Genome annotation databases

EnsemblBacteriaiABB35807; ABB35807; Syncc9605_2067.
KEGGisyd:Syncc9605_2067.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000110 Genomic DNA. Translation: ABB35807.1.
RefSeqiWP_011365016.1. NC_007516.1.

3D structure databases

ProteinModelPortaliQ3AHX5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi110662.Syncc9605_2067.

Proteomic databases

PRIDEiQ3AHX5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB35807; ABB35807; Syncc9605_2067.
KEGGisyd:Syncc9605_2067.

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Enzyme and pathway databases

BioCyciSSP110662:GJ7R-2114-MONOMER.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Synechococcus sp. CC9605."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CC9605.

Entry informationi

Entry nameiRPOB_SYNSC
AccessioniPrimary (citable) accession number: Q3AHX5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 22, 2005
Last modified: November 11, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.