Reviewed, UniProtKB/Swiss-Prot Q3AHV1 (GLUQ_SYNSC)

Names and origin

Protein names

Recommended name:
    Glutamyl-Q tRNA(Asp) synthetase
      Short name=Glu-Q-RSs
    EC=6.1.1.-

Gene names

Name:	gluQ
Ordered Locus Names:	Syncc9605_2091

Organism

Synechococcus sp. (strain CC9605) [Complete proteome] [HAMAP]

Taxonomic identifier

110662 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon By similarity.
Cofactor	Binds 1 zinc ion per subunit By similarity.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.

Ontologies

Keywords
Ligand	ATP-binding Metal-binding Nucleotide-binding Zinc
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA aminoacylation for protein translation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW aminoacyl-tRNA ligase activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 293	293	Glutamyl-Q tRNA(Asp) synthetase HAMAP MF_01428		PRO_1000024369
Regions
	Region	26 – 30	5	Glutamate binding By similarity
	Motif	29 – 39	11	"HIGH" region HAMAP MF_01428
	Motif	234 – 238	5	"KMSKS" region HAMAP MF_01428
Sites
	Metal binding	118	1	Zinc By similarity
	Metal binding	120	1	Zinc By similarity
	Metal binding	131	1	Zinc By similarity
	Metal binding	135	1	Zinc By similarity
	Binding site	62	1	Glutamate By similarity
	Binding site	178	1	Glutamate By similarity
	Binding site	196	1	Glutamate By similarity
	Binding site	237	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3AHV1-1 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: AEADA4C965B14501	FASTA	293	32,232
	10 20 30 40 50 60 MALPEHLQRH LEAGRALTAA GGYRGRFAPS PTGLLHLGNL QTALLSWLAA RQAGGAWLLR 70 80 90 100 110 120 IDDLDTPRNR AGAIEAIQSD LRWLGLKWDG PVLLQSERRG IYHSWLSWLR RSGRLFACRC 130 140 150 160 170 180 SRRELADQPI YSGFCRQAVH NWGWQRQRLP SWRLRVADDD PHGSGDVVLR RADGFIAYQL 190 200 210 220 230 240 ATVIDELSFG INDVVRGADL REALPAQRSL FAALGEAPPR FRHGPLLCDA SGQKLSKREA 250 260 270 280 290 CAGLKPLRDA GLDAAAVIGR LASGLQLVAP EARISATELL EHLTQQAINA VIS

References

[1]

"Complete sequence of Synechococcus sp. CC9605." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000110 Genomic DNA. Translation: ABB35831.1.
RefSeq	YP_382386.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q3AHV1.
Genome annotation databases
GeneID	3736278.
GenomeReviews	Gene locus Syncc9605_2091 in contig CP000110_GR.
KEGG	syd:Syncc9605_2091.
NMPDR	fig|110662.3.peg.1354.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3AHV1.
OMA	QPVRRQS.
Enzyme and pathway databases
BioCyc	SSP1131:SYNCC9605_2091-MON.
Family and domain databases
HAMAP	MF_01428. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR000924. Glu/Gln-tRNA-synth_Ic. IPR020058. Glu/Gln-tRNA-synth_Ic_cat-dom. IPR020060. Glu/Gln-tRNA-synth_Ic_N. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR10119. Glu_tRNA-synt_1c. 1 hit.
Pfam	PF00749. tRNA-synt_1c. 2 hits. [Graphical view]
PRINTS	PR00987. TRNASYNTHGLU.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLUQ_SYNSC

Accession

Primary (citable) accession number: Q3AHV1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 22, 2005
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)