SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q3AHU2

- PYRF_SYNSC

UniProt

Q3AHU2 - PYRF_SYNSC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Orotidine 5'-phosphate decarboxylase
Gene
pyrF, Syncc9605_2100
Organism
Synechococcus sp. (strain CC9605)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP) By similarity.UniRule annotation

Catalytic activityi

Orotidine 5'-phosphate = UMP + CO2.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei18 – 181Substrate By similarity
Binding sitei39 – 391Substrate By similarity
Active sitei68 – 681Proton donor By similarity
Binding sitei130 – 1301Substrate By similarity
Binding sitei192 – 1921Substrate By similarity
Binding sitei201 – 2011Substrate By similarity
Binding sitei221 – 2211Substrate; via amide nitrogen By similarity
Binding sitei222 – 2221Substrate By similarity

GO - Molecular functioni

  1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Pyrimidine biosynthesis

Enzyme and pathway databases

BioCyciSSP110662:GJ7R-2149-MONOMER.
UniPathwayiUPA00070; UER00120.

Names & Taxonomyi

Protein namesi
Recommended name:
Orotidine 5'-phosphate decarboxylase (EC:4.1.1.23)
Alternative name(s):
OMP decarboxylase
Short name:
OMPDCase
Short name:
OMPdecase
Gene namesi
Name:pyrF
Ordered Locus Names:Syncc9605_2100
OrganismiSynechococcus sp. (strain CC9605)
Taxonomic identifieri110662 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
ProteomesiUP000002711: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 241241Orotidine 5'-phosphate decarboxylaseUniRule annotation
PRO_0000241917Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi110662.Syncc9605_2100.

Structurei

3D structure databases

ProteinModelPortaliQ3AHU2.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni66 – 7510Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0284.
HOGENOMiHOG000226070.
KOiK01591.
OMAiDIPNTMR.
OrthoDBiEOG6N6815.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01200_B. OMPdecase_type1_B.
InterProiIPR013785. Aldolase_TIM.
IPR014732. OMPdecase.
IPR018089. OMPdecase_AS.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR01740. pyrF. 1 hit.
PROSITEiPS00156. OMPDECASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3AHU2-1 [UniParc]FASTAAdd to Basket

« Hide

MAPTLSADPA DRIIVALDGM APDQALRFAA HVDGLRWVKV GLELFVQAGP    50
EVVAQLREQG LRVFLDLKFH DIPATMAGAC RRAAALGAEL ITVHACAGSE 100
ALKAVKVAAE EGAQAAGQPA PTLLAVTVLT SWEEQRLQRE LAIAQGIAER 150
VPALAQLSAT AGIGGCVCSP LEAAALRAQH PQPFALVTPG IRPRGAAVGD 200
QARVMGPAEA IAAGASQLVI GRPISKAEDP SAAFAACCGD L 241
Length:241
Mass (Da):24,684
Last modified:November 22, 2005 - v1
Checksum:i387642D6880C75E3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000110 Genomic DNA. Translation: ABB35840.1.
RefSeqiWP_011365048.1. NC_007516.1.
YP_382395.1. NC_007516.1.

Genome annotation databases

EnsemblBacteriaiABB35840; ABB35840; Syncc9605_2100.
GeneIDi3736288.
KEGGisyd:Syncc9605_2100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000110 Genomic DNA. Translation: ABB35840.1 .
RefSeqi WP_011365048.1. NC_007516.1.
YP_382395.1. NC_007516.1.

3D structure databases

ProteinModelPortali Q3AHU2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 110662.Syncc9605_2100.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABB35840 ; ABB35840 ; Syncc9605_2100 .
GeneIDi 3736288.
KEGGi syd:Syncc9605_2100.

Phylogenomic databases

eggNOGi COG0284.
HOGENOMi HOG000226070.
KOi K01591.
OMAi DIPNTMR.
OrthoDBi EOG6N6815.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00120 .
BioCyci SSP110662:GJ7R-2149-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_01200_B. OMPdecase_type1_B.
InterProi IPR013785. Aldolase_TIM.
IPR014732. OMPdecase.
IPR018089. OMPdecase_AS.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00215. OMPdecase. 1 hit.
[Graphical view ]
SMARTi SM00934. OMPdecase. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
TIGRFAMsi TIGR01740. pyrF. 1 hit.
PROSITEi PS00156. OMPDECASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Synechococcus sp. CC9605."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CC9605.

Entry informationi

Entry nameiPYRF_SYNSC
AccessioniPrimary (citable) accession number: Q3AHU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 22, 2005
Last modified: September 3, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi