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Q3AH68 (UPPP_SYNSC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Syncc9605_2332
OrganismSynechococcus sp. (strain CC9605) [Complete proteome] [HAMAP]
Taxonomic identifier110662 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length287 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 287287Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000250272

Regions

Transmembrane50 – 7021Helical; Potential
Transmembrane97 – 11721Helical; Potential
Transmembrane131 – 15121Helical; Potential
Transmembrane160 – 18021Helical; Potential
Transmembrane206 – 22621Helical; Potential
Transmembrane234 – 25421Helical; Potential
Transmembrane264 – 28421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q3AH68 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 7B275EC8A4904D27

FASTA28730,539
        10         20         30         40         50         60 
MADPSASLNL VEACWRDLVL GVVQGLTEFL PISSTAHLKV VPELLGWGDP GVSVTAAIQL 

        70         80         90        100        110        120 
GSIAAVIAYF RTDLSQVLRG VSRAFRYGQW REPEARLGFA MVVGTLPILV IGLGIKFAWS 

       130        140        150        160        170        180 
QGYEQSPLRS IPSIAIVSIV MALLLALAEQ VGARSKQLDV VLGRDGLLVG LAQALALLPG 

       190        200        210        220        230        240 
VSRSGSTLTA ALFDGWQRAD AARFSFLLGI PGITIAGLVE LKDALAASPG NGPLPLLVGI 

       250        260        270        280 
GSAAVVSWLA IDWLLKFLQR NSTWLFVAYR LVFGLLLLVW WGVYGSH 

« Hide

References

[1]"Complete sequence of Synechococcus sp. CC9605."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CC9605.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000110 Genomic DNA. Translation: ABB36064.1.
RefSeqYP_382619.1. NC_007516.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING110662.Syncc9605_2332.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB36064; ABB36064; Syncc9605_2332.
GeneID3736685.
KEGGsyd:Syncc9605_2332.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycSSP110662:GJ7R-2389-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_SYNSC
AccessionPrimary (citable) accession number: Q3AH68
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: November 22, 2005
Last modified: February 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families