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Q3AFH3

- G6PI_CARHZ

UniProt

Q3AFH3 - G6PI_CARHZ

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, CHY_0239
Organism
Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei290 – 2901Proton donor By similarity
Active sitei319 – 3191 By similarity
Active sitei433 – 4331 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCHYD246194:GJCN-240-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:CHY_0239
OrganismiCarboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)
Taxonomic identifieri246194 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCarboxydothermus
ProteomesiUP000002706: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 464464Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000230915Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi246194.CHY_0239.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100402.
KOiK01810.
OMAiQVIFIGN.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3AFH3-1 [UniParc]FASTAAdd to Basket

« Hide

MALKIDFNNV FHPYLQKERL GEADIDGYKE KFTSALVSLR EKKEKGELGF    50
FHLPYLPEEE IAEIEKTARE VREKFKYFVV LGIGGSALGP LAVHTALNNL 100
RYNELSEELR GGPKFYVEDN IDPERMASLL KVIEPEKTVF NVITKSGATA 150
ETLSQLLIVT EVLKKKVGKR FTEHLIFTTD PEKGSLRALA RELGVKTFAI 200
PPNVGGRFSE LTPVGLLPAA VTGINIRELL AGAREMAERC ERENLWENPA 250
GLAAAIHVLL LERGKNMAVM MPYADSLKYM ADWYAQLLGE SIGKRLNRRG 300
EEVFVGQTPV KALGVTDQHS QVQLYTEGPF DKLLIFLEVE RYRNRVVIPP 350
DFPQYAELKF LGGHTLNELI IAEKKATEFA LLKARRPNYT VIFPEVNPYT 400
VGELLYFLEA KIAFMGEYLD INAFDQPGVE EGKKATYALL GREGFEEKRQ 450
EVLKVKKEPR FILE 464
Length:464
Mass (Da):52,456
Last modified:November 22, 2005 - v1
Checksum:iF8F6C53153B03221
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000141 Genomic DNA. Translation: ABB14260.1.
RefSeqiWP_011343187.1. NC_007503.1.
YP_359111.1. NC_007503.1.

Genome annotation databases

EnsemblBacteriaiABB14260; ABB14260; CHY_0239.
GeneIDi3728629.
KEGGichy:CHY_0239.
PATRICi21273659. VBICarHyd26463_0229.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000141 Genomic DNA. Translation: ABB14260.1 .
RefSeqi WP_011343187.1. NC_007503.1.
YP_359111.1. NC_007503.1.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 246194.CHY_0239.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABB14260 ; ABB14260 ; CHY_0239 .
GeneIDi 3728629.
KEGGi chy:CHY_0239.
PATRICi 21273659. VBICarHyd26463_0229.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100402.
KOi K01810.
OMAi QVIFIGN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci CHYD246194:GJCN-240-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Z-2901 / DSM 6008.

Entry informationi

Entry nameiG6PI_CARHZ
AccessioniPrimary (citable) accession number: Q3AFH3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: November 22, 2005
Last modified: September 3, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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