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Q3AFH3

- G6PI_CARHZ

UniProt

Q3AFH3 - G6PI_CARHZ

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (22 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei290 – 2901Proton donorUniRule annotation
    Active sitei319 – 3191UniRule annotation
    Active sitei433 – 4331UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciCHYD246194:GJCN-240-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:CHY_0239
    OrganismiCarboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)
    Taxonomic identifieri246194 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCarboxydothermus
    ProteomesiUP000002706: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 464464Glucose-6-phosphate isomerasePRO_0000230915Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi246194.CHY_0239.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100402.
    KOiK01810.
    OMAiQVIFIGN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3AFH3-1 [UniParc]FASTAAdd to Basket

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    MALKIDFNNV FHPYLQKERL GEADIDGYKE KFTSALVSLR EKKEKGELGF    50
    FHLPYLPEEE IAEIEKTARE VREKFKYFVV LGIGGSALGP LAVHTALNNL 100
    RYNELSEELR GGPKFYVEDN IDPERMASLL KVIEPEKTVF NVITKSGATA 150
    ETLSQLLIVT EVLKKKVGKR FTEHLIFTTD PEKGSLRALA RELGVKTFAI 200
    PPNVGGRFSE LTPVGLLPAA VTGINIRELL AGAREMAERC ERENLWENPA 250
    GLAAAIHVLL LERGKNMAVM MPYADSLKYM ADWYAQLLGE SIGKRLNRRG 300
    EEVFVGQTPV KALGVTDQHS QVQLYTEGPF DKLLIFLEVE RYRNRVVIPP 350
    DFPQYAELKF LGGHTLNELI IAEKKATEFA LLKARRPNYT VIFPEVNPYT 400
    VGELLYFLEA KIAFMGEYLD INAFDQPGVE EGKKATYALL GREGFEEKRQ 450
    EVLKVKKEPR FILE 464
    Length:464
    Mass (Da):52,456
    Last modified:November 22, 2005 - v1
    Checksum:iF8F6C53153B03221
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000141 Genomic DNA. Translation: ABB14260.1.
    RefSeqiWP_011343187.1. NC_007503.1.
    YP_359111.1. NC_007503.1.

    Genome annotation databases

    EnsemblBacteriaiABB14260; ABB14260; CHY_0239.
    GeneIDi3728629.
    KEGGichy:CHY_0239.
    PATRICi21273659. VBICarHyd26463_0229.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000141 Genomic DNA. Translation: ABB14260.1 .
    RefSeqi WP_011343187.1. NC_007503.1.
    YP_359111.1. NC_007503.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 246194.CHY_0239.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB14260 ; ABB14260 ; CHY_0239 .
    GeneIDi 3728629.
    KEGGi chy:CHY_0239.
    PATRICi 21273659. VBICarHyd26463_0229.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100402.
    KOi K01810.
    OMAi QVIFIGN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci CHYD246194:GJCN-240-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Z-2901 / DSM 6008.

    Entry informationi

    Entry nameiG6PI_CARHZ
    AccessioniPrimary (citable) accession number: Q3AFH3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3