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Protein

Adenine deaminase 2

Gene

ade2

Organism
Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciCHYD246194:GJCN-699-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminase 2UniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
Adenase 2UniRule annotation
Short name:
Adenine aminase 2UniRule annotation
Gene namesi
Name:ade2UniRule annotation
Ordered Locus Names:CHY_0699
OrganismiCarboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)
Taxonomic identifieri246194 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCarboxydothermus
Proteomesi
  • UP000002706 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 570570Adenine deaminase 2PRO_0000292378Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi246194.CHY_0699.

Structurei

3D structure databases

ProteinModelPortaliQ3AE81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiPOG091H00I8.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3AE81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPIKDLVEV ALGKKPADLV LKNAQVFNSF TGEFVTGDVA VVAGYIAGTG
60 70 80 90 100
EYEGKTTYDL QGAYVTPGFI DGHVHIESSM VAPAEFARAL VPAGTLTAVV
110 120 130 140 150
DPHEIANVSG TAGIRYMLEA SSNLPINIYL MLPSCVPATS LETAGAVLTA
160 170 180 190 200
RELSEFINHP RVLGLGELMD YPGVLNTHEE MLKKLAVTEG KLIDGHAPGI
210 220 230 240 250
SGKELTAYIA AGVNSEHECT TAEEARERLS RGMYLMLREG SATKNLLDLL
260 270 280 290 300
PAVDRYTASR CFFVTDDRHP EDLIKLGSIN HMVKLAVSAG ADLPTVLQMA
310 320 330 340 350
TINAANYFRL YDLGAIAPGY RADILVFEDL QEFKPKYVFK DGKLVAENGK
360 370 380 390 400
PLFTGYPVDD RAVRNTMRLK EINPEKLKIP AKSNRARVIG LIPHQIVTKK
410 420 430 440 450
LELEVPVEGG YFKTSTEKDI AKLAVFERHN YTGNVGVGLI HGLGLKKGAI
460 470 480 490 500
ASTVAHDSHN LVVAGMSDED IIAAVEELKR IGGGLTVVAD GQVLGSLPLP
510 520 530 540 550
IAGLMSDRTL YEVQEELEKL HRIVRNLGVS ENYDPFMTLA FLSLPVIPEL
560 570
KLTDLGLVDV STFSVVPVSL
Length:570
Mass (Da):61,600
Last modified:November 22, 2005 - v1
Checksum:i47EFFF8C00F1B291
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000141 Genomic DNA. Translation: ABB15047.1.
RefSeqiWP_011343629.1. NC_007503.1.

Genome annotation databases

EnsemblBacteriaiABB15047; ABB15047; CHY_0699.
KEGGichy:CHY_0699.
PATRICi21274533. VBICarHyd26463_0654.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000141 Genomic DNA. Translation: ABB15047.1.
RefSeqiWP_011343629.1. NC_007503.1.

3D structure databases

ProteinModelPortaliQ3AE81.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246194.CHY_0699.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB15047; ABB15047; CHY_0699.
KEGGichy:CHY_0699.
PATRICi21274533. VBICarHyd26463_0654.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiPOG091H00I8.

Enzyme and pathway databases

BioCyciCHYD246194:GJCN-699-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADEC2_CARHZ
AccessioniPrimary (citable) accession number: Q3AE81
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: November 22, 2005
Last modified: September 7, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.