Reviewed, UniProtKB/Swiss-Prot Q3AD96 (COMB_CARHZ)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	CHY_1042

Organism

Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) [Complete proteome] [HAMAP]

Taxonomic identifier

246194 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacteriaceae › Carboxydothermus

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 238	238	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000072426

Sequences

	Sequence		Length	Mass (Da)
	Q3AD96-1 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: C0E9F95365049550	FASTA	238	25,782
	10 20 30 40 50 60 MKIDVLFYPE KLKNAEDKAV VVLDVLRATT TIATALAAGA EKIYPVSSIK EAFLLKKKIS 70 80 90 100 110 120 GALLGGERGG IKVPGFDLGN SPLEYQGLKG KTIILSSTNG TKTLKKAVSA RTLIAGSIVN 130 140 150 160 170 180 AKAVADYLLK LNLDVVLMPS GTDSQFSLED FAGAGYIISL LAEQKKIELS DQAYVSFELA 190 200 210 220 230 RSNPPEEILT RSFHGQRLIN LGFARDVEYC AKLNLLDVVP EGHLQEGRLV IESSRLFR

References

[1]

"Life in hot carbon monoxide: the complete genome sequence of Carboxydothermus hydrogenoformans Z-2901." Wu M., Ren Q., Durkin A.S., Daugherty S.C., Brinkac L.M., Dodson R.J., Madupu R., Sullivan S.A., Kolonay J.F., Nelson W.C., Tallon L.J., Jones K.M., Ulrich L.E., Gonzalez J.M., Zhulin I.B., Robb F.T., Eisen J.A. PLoS Genet. 1:563-574(2005) [PubMed: 16311624] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000141 Genomic DNA. Translation: ABB15297.1.
RefSeq	YP_359888.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3727400.
GenomeReviews	Gene locus CHY_1042 in contig CP000141_GR.
KEGG	chy:CHY_1042.
NMPDR	fig|246194.3.peg.725.
TIGR	CHY_1042.
Phylogenomic databases
HOGENOM	Q3AD96.
OMA	Q3AD96. DFICSGY.
Enzyme and pathway databases
BioCyc	CHYD246194:CHY_1042-MON.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
TIGRFAMs	TIGR00298. 2-ph_phosphatase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_CARHZ

Accession

Primary (citable) accession number: Q3AD96

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	November 22, 2005
Last modified:	May 5, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)