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Protein
Submitted name:

CO dehydrogenase/acetyl-CoA synthase, iron-sulfur protein

Gene

acsD

Organism
Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciCHYD246194:GJCN-1225-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
CO dehydrogenase/acetyl-CoA synthase, iron-sulfur proteinImported
Gene namesi
Name:acsDImported
Ordered Locus Names:CHY_1226Imported
OrganismiCarboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)Imported
Taxonomic identifieri246194 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCarboxydothermus
Proteomesi
  • UP000002706 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

DIPiDIP-61273N.
STRINGi246194.CHY_1226.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2H9AX-ray1.90B1-310[»]
2YCLX-ray1.95B1-310[»]
4C1NX-ray2.53B/D/F/H2-310[»]
ProteinModelPortaliQ3ACS0.
SMRiQ3ACS0. Positions 3-309.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ3ACS0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 264249CdhDInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4106HYN. Bacteria.
COG2069. LUCA.
HOGENOMiHOG000224315.
KOiK00194.
OMAiIEINEFR.
OrthoDBiEOG6R5C48.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR016041. Ac-CoA_synth_d_su_TIM-brl.
IPR013785. Aldolase_TIM.
IPR011005. Dihydropteroate_synth-like.
[Graphical view]
PfamiPF03599. CdhD. 1 hit.
[Graphical view]
SUPFAMiSSF51717. SSF51717. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3ACS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVEVLKEKW NSKVVEVTLG TGDKTVTLGG DSTLPFLTFE GEMPNPPRFA
60 70 80 90 100
LEVFDTPPTD WPDILVEPFK DVINDPVAWA KKCVEYGADI VALRLVSAHP
110 120 130 140 150
DGQNRSGAEL AEVCKAVADA IDVPLMIIGC GVEEKDAEIF PVIGEALSGR
160 170 180 190 200
NCLLSSATKD NYKPIVATCM VHGHSVVASA PLDINLSKQL NIMIMEMNLA
210 220 230 240 250
PNRIIMDPLI GALGYGIEYS YSIIERMRLG ALTGDKILAM PVVCFIGQEA
260 270 280 290 300
WKAKEAKDPE VAEWGDYALR AIHWETVTTV ALIQAGGHLF VMRHPKSLAE
310
VKEHLKRILK
Length:310
Mass (Da):33,873
Last modified:November 22, 2005 - v1
Checksum:iBFA35215916D77D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000141 Genomic DNA. Translation: ABB13976.1.
RefSeqiWP_011344140.1. NC_007503.1.

Genome annotation databases

EnsemblBacteriaiABB13976; ABB13976; CHY_1226.
KEGGichy:CHY_1226.
PATRICi21275591. VBICarHyd26463_1172.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000141 Genomic DNA. Translation: ABB13976.1.
RefSeqiWP_011344140.1. NC_007503.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2H9AX-ray1.90B1-310[»]
2YCLX-ray1.95B1-310[»]
4C1NX-ray2.53B/D/F/H2-310[»]
ProteinModelPortaliQ3ACS0.
SMRiQ3ACS0. Positions 3-309.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-61273N.
STRINGi246194.CHY_1226.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB13976; ABB13976; CHY_1226.
KEGGichy:CHY_1226.
PATRICi21275591. VBICarHyd26463_1172.

Phylogenomic databases

eggNOGiENOG4106HYN. Bacteria.
COG2069. LUCA.
HOGENOMiHOG000224315.
KOiK00194.
OMAiIEINEFR.
OrthoDBiEOG6R5C48.

Enzyme and pathway databases

BioCyciCHYD246194:GJCN-1225-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ3ACS0.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR016041. Ac-CoA_synth_d_su_TIM-brl.
IPR013785. Aldolase_TIM.
IPR011005. Dihydropteroate_synth-like.
[Graphical view]
PfamiPF03599. CdhD. 1 hit.
[Graphical view]
SUPFAMiSSF51717. SSF51717. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-161 / DSM 6008 / Z-2901Imported.
  2. "Structural insights into methyltransfer reactions of a corrinoid iron-sulfur protein involved in acetyl-CoA synthesis."
    Svetlitchnaia T., Svetlitchnyi V., Meyer O., Dobbek H.
    Proc. Natl. Acad. Sci. U.S.A. 103:14331-14336(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS).
  3. "Structural basis for electron and methyl-group transfer in a methyltransferase system operating in the reductive acetyl-CoA pathway."
    Goetzl S., Jeoung J.H., Hennig S.E., Dobbek H.
    J. Mol. Biol. 411:96-109(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS).
  4. "ATP-induced electron transfer by redox-selective partner recognition."
    Hennig S.E., Goetzl S., Jeoung J.H., Bommer M., Lendzian F., Hildebrandt P., Dobbek H.
    Nat. Commun. 5:4626-4626(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.53 ANGSTROMS) OF 2-310.

Entry informationi

Entry nameiQ3ACS0_CARHZ
AccessioniPrimary (citable) accession number: Q3ACS0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: July 6, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.