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Q3AB72

- Q3AB72_CARHZ

UniProt

Q3AB72 - Q3AB72_CARHZ

Protein

Tyrosine recombinase XerC

Gene

xerC

Organism
Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (22 Nov 2005)
      Previous versions | rss
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    Functioni

    Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei143 – 1431UniRule annotation
    Active sitei167 – 1671UniRule annotation
    Active sitei236 – 2361UniRule annotation
    Active sitei239 – 2391UniRule annotation
    Active sitei262 – 2621UniRule annotation
    Active sitei271 – 2711O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. tyrosine-based site-specific recombinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. chromosome segregation Source: UniProtKB-HAMAP
    4. transposition, DNA-mediated Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Cell cycle, Cell divisionUniRule annotationSAAS annotation, Chromosome partitionUniRule annotationSAAS annotation, DNA integrationUniRule annotationSAAS annotation, DNA recombinationUniRule annotationSAAS annotation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCHYD246194:GJCN-1791-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tyrosine recombinase XerCUniRule annotation
    Gene namesi
    Name:xerCUniRule annotationImported
    Ordered Locus Names:CHY_1792Imported
    OrganismiCarboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)Imported
    Taxonomic identifieri246194 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCarboxydothermus
    ProteomesiUP000002706: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.UniRule annotation

    Protein-protein interaction databases

    STRINGi246194.CHY_1792.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3AB72.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the 'phage' integrase family. XerC subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG4974.
    HOGENOMiHOG000045294.
    KOiK03733.
    OMAiIYTHIVS.
    OrthoDBiEOG6PZXFP.

    Family and domain databases

    Gene3Di1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPiMF_01808. Recomb_XerC.
    InterProiIPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR011932. Recomb_XerD.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view]
    PfamiPF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56349. SSF56349. 1 hit.
    TIGRFAMsiTIGR02225. recomb_XerD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3AB72-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEELKAFLN YLLLERNYSP NTIAAYERDI LDFQEFLQGK SFLSVNEVDL    50
    KQFLVDILRK NRSRRTAARK MVALRSFYRF LKRCGFIKEN PALSLEIPKI 100
    PKTLPEVLTV DEVFKVIEGQ ENSTPTGLRN RALLELFYGA GLRIGEIAGL 150
    TLNDLDLTQG YVRVTGKGRR QRIVPLGKYA LDSLKLYLEA GRPAFKPKSE 200
    KLFLNQQGAG LTVRGIRYLI SQIVKKAGLN RKITPHTFRH SYATHLLEGG 250
    ADIRAVQELL GHKRLSTTEI YTHLSKERLR EVYLRTHPRS REEKNDV 297
    Length:297
    Mass (Da):34,072
    Last modified:November 22, 2005 - v1
    Checksum:iCE718CACD3458A37
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000141 Genomic DNA. Translation: ABB15009.1.
    RefSeqiYP_360612.1. NC_007503.1.

    Genome annotation databases

    EnsemblBacteriaiABB15009; ABB15009; CHY_1792.
    GeneIDi3726230.
    KEGGichy:CHY_1792.
    PATRICi21276695. VBICarHyd26463_1711.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000141 Genomic DNA. Translation: ABB15009.1 .
    RefSeqi YP_360612.1. NC_007503.1.

    3D structure databases

    ProteinModelPortali Q3AB72.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 246194.CHY_1792.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB15009 ; ABB15009 ; CHY_1792 .
    GeneIDi 3726230.
    KEGGi chy:CHY_1792.
    PATRICi 21276695. VBICarHyd26463_1711.

    Phylogenomic databases

    eggNOGi COG4974.
    HOGENOMi HOG000045294.
    KOi K03733.
    OMAi IYTHIVS.
    OrthoDBi EOG6PZXFP.

    Enzyme and pathway databases

    BioCyci CHYD246194:GJCN-1791-MONOMER.

    Family and domain databases

    Gene3Di 1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPi MF_01808. Recomb_XerC.
    InterProi IPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR011932. Recomb_XerD.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view ]
    Pfami PF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56349. SSF56349. 1 hit.
    TIGRFAMsi TIGR02225. recomb_XerD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Z-2901 / DSM 6008Imported.

    Entry informationi

    Entry nameiQ3AB72_CARHZ
    AccessioniPrimary (citable) accession number: Q3AB72
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 22, 2005
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3