Reviewed, UniProtKB/Swiss-Prot Q3AAF7 (SELD_CARHZ)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase
    Selenium donor protein

Gene names

Name:	selD
Ordered Locus Names:	CHY_2058

Organism

Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) [Complete proteome] [HAMAP]

Taxonomic identifier

246194 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacteriaceae › Carboxydothermus

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity. HAMAP MF_00625
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity. HAMAP MF_00625
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.

Ontologies

Keywords
Coding sequence diversity	Selenocysteine
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Selenide, water dikinase HAMAP MF_00625		PRO_1000051596
Regions
	Nucleotide binding	226 – 232	7	ATP Potential
Sites
	Active site	15	1	Potential
	Site	18	1	Important for catalytic activity By similarity
Amino acid modifications
	Non-standard residue	15	1	Selenocysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	Q3AAF7-1 [UniParc]. Last modified February 26, 2008. Version 2. Checksum: A4BBD8815ACDB77E	FASTA	343	36,685
	10 20 30 40 50 60 MEAVKLTQLV SCAGUAAKMS PETLAQVLRY LPEINDPNAL VGTNTADDAA VYRISDEQAI 70 80 90 100 110 120 VLTVDYFTPV VDDPYYFGVI AAANSLSDIY AMGAKPLFAL NVVGFPKKLP PEILATILKG 130 140 150 160 170 180 GADKAREAGI PVLGGHTVDD AEPKYGMVVC GLVHPDKIVK NHPPHPGDSL ILTKPLGIGV 190 200 210 220 230 240 LTTGMKRGIV PENTAKKVME VMETLNDKAA EVMVEVGVSA ATDITGFGLL GHLKEMLQEE 250 260 270 280 290 300 FGAEIYLTKI PAIEGAWEFA GMRVFPGGAK NNLNYLLPHL DFAGEFAEEE KLFLADPQTS 310 320 330 340 GGLLMAVSQE KKEELVKKLQ QKGVLAAEIG IITGNKGKIV VKR

References

[1]

"Life in hot carbon monoxide: the complete genome sequence of Carboxydothermus hydrogenoformans Z-2901." Wu M., Ren Q., Durkin A.S., Daugherty S.C., Brinkac L.M., Dodson R.J., Madupu R., Sullivan S.A., Kolonay J.F., Nelson W.C., Tallon L.J., Jones K.M., Ulrich L.E., Gonzalez J.M., Zhulin I.B., Robb F.T., Eisen J.A. PLoS Genet. 1:563-574(2005) [PubMed: 16311624] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000141 Genomic DNA. Translation: ABB15977.1.
RefSeq	YP_360877.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q3AAF7.
Genome annotation databases
GeneID	3728088.
GenomeReviews	Gene locus CHY_2058 in contig CP000141_GR.
KEGG	chy:CHY_2058.
TIGR	CHY_2058.
Phylogenomic databases
eggNOG	COG0709.
HOGENOM	HBG383791.
OMA	GGTQRNF.
Enzyme and pathway databases
BioCyc	CHYD246194:CHY_2058-MONOMER.
Family and domain databases
HAMAP	MF_00625. SelD. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR016188. PurM_N-like. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_CARHZ

Accession

Primary (citable) accession number: Q3AAF7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 26, 2008
Last modified:	February 9, 2010
This is version 26 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)