ID   Q3A742_SYNC1            Unreviewed;       676 AA.
AC   Q3A742;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer, class 36H, Cache_1 domain-containing {ECO:0000313|EMBL:ABA87805.1};
GN   Name=mcp36H-2 {ECO:0000313|EMBL:ABA87805.1};
GN   OrderedLocusNames=Pcar_0545 {ECO:0000313|EMBL:ABA87805.1};
OS   Syntrophotalea carbinolica (strain DSM 2380 / NBRC 103641 / GraBd1)
OS   (Pelobacter carbinolicus).
OC   Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Desulfuromonadales;
OC   Syntrophotaleaceae; Syntrophotalea.
OX   NCBI_TaxID=338963 {ECO:0000313|EMBL:ABA87805.1, ECO:0000313|Proteomes:UP000002534};
RN   [1] {ECO:0000313|Proteomes:UP000002534}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2380 / NBRC 103641 / GraBd1
RC   {ECO:0000313|Proteomes:UP000002534};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Pelobacter carbinolicus DSM 2380.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABA87805.1, ECO:0000313|Proteomes:UP000002534}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2380 / NBRC 103641 / GraBd1
RC   {ECO:0000313|Proteomes:UP000002534};
RX   PubMed=23227809; DOI=10.1186/1471-2164-13-690;
RA   Aklujkar M., Haveman S.A., Didonato R.Jr., Chertkov O., Han C.S.,
RA   Land M.L., Brown P., Lovley D.R.;
RT   "The genome of Pelobacter carbinolicus reveals surprising metabolic
RT   capabilities and physiological features.";
RL   BMC Genomics 13:690-690(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000142; ABA87805.1; -; Genomic_DNA.
DR   RefSeq; WP_011340243.1; NC_007498.2.
DR   AlphaFoldDB; Q3A742; -.
DR   STRING; 338963.Pcar_0545; -.
DR   KEGG; pca:Pcar_0545; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_12_7; -.
DR   Proteomes; UP000002534; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd12914; PDC1_DGC_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002534};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        288..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          307..359
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          403..632
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          654..676
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   676 AA;  71973 MW;  6D5E27958F7B06AD CRC64;
     MTLNLRGKIL LPTIIVVVVG LALSGFLNYR SSKAALETTI NGQLTELTRG LAGQFEGWID
     GLIHDIEICS QRDVMRRALQ AEGEDQQLAT LDAGKDLETM LKEYGGYEGF HVAGIDGRVV
     ASSDPAAVGK LDISQRDYFK QSLAGKTIVS EVLRSKVTNN PIFVIAVPVH DGTRVAGVII
     GVLDLLQFTD QYIKPVKIGQ RGYVYVLDGQ GRFIAHPNGS NILNVNVAGY DWGQEVLGKK
     RGFTFYQWEG IDKLLAYDQV PSTGWIVAAC AENHDVFSAI DGIRNQSILV ALILLGVLIG
     VVFLIVRPIV NAVRLGAHFA ETISLGDLSE RLHLARQDEI GQLGQALDTM ADSLQEKARL
     ADQIAQGNLA VEVSLASDKD QLGKALQGMT ANLNEVLGEV NVAGEYIASC AAQVSDSSQS
     LSQSATEAAA SMEEITASMT EMASQTRLNA ENAEQANELS KEAHGGATQG AELMEKMLAA
     IWDINASSED ISKIIKVIDE IAFQTNLLAL NAAVEAARAG QHGKGFAVVA EEVRTLAARS
     AKAAKETAEL IENSVAKTRN GTELADKTSA SLQTIVDGAT KVSDLVAEIS MASNEQAQGF
     NQVNMGLGQI DGVTQQNTAN AEESAAAAQE LTGQAERLQH VLARFTLASA QASRRSAAGQ
     KDISIEAQQK LALPPA
//