UniProtKB - Q3A6K6 (SYR_PELCD)
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Protein
Arginine--tRNA ligase
Gene
argS
Organism
Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1)
Status
Functioni
Catalytic activityi
ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation
GO - Molecular functioni
- arginine-tRNA ligase activity Source: UniProtKB-EC
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- arginyl-tRNA aminoacylation Source: InterPro
Keywordsi
Molecular function | Aminoacyl-tRNA synthetase, Ligase |
Biological process | Protein biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | PCAR338963:G1G5C-786-MONOMER. |
Names & Taxonomyi
Protein namesi | Recommended name: Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)Alternative name(s): Arginyl-tRNA synthetaseUniRule annotation Short name: ArgRSUniRule annotation |
Gene namesi | Name:argSUniRule annotation Ordered Locus Names:Pcar_0742 |
Organismi | Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1) |
Taxonomic identifieri | 338963 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Desulfuromonadaceae › Pelobacter › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000242062 | 1 – 554 | Arginine--tRNA ligaseAdd BLAST | 554 |
Interactioni
Subunit structurei
Monomer.UniRule annotation
Protein-protein interaction databases
STRINGi | 338963.Pcar_0742. |
Structurei
3D structure databases
ProteinModelPortali | Q3A6K6. |
SMRi | Q3A6K6. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 129 – 139 | "HIGH" regionAdd BLAST | 11 |
Sequence similaritiesi
Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG4105C75. Bacteria. COG0018. LUCA. |
HOGENOMi | HOG000247214. |
KOi | K01887. |
OMAi | NKPLHLG. |
OrthoDBi | POG091H01RF. |
Family and domain databases
CDDi | cd00671. ArgRS_core. 1 hit. |
Gene3Di | 3.30.1360.70. 1 hit. 3.40.50.620. 1 hit. |
HAMAPi | MF_00123. Arg_tRNA_synth. 1 hit. |
InterProi | View protein in InterPro IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase. IPR005148. Arg-tRNA-synth_N. IPR036695. Arg-tRNA-synth_N_sf. IPR035684. ArgRS_core. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_Ia_anticodon-bd. |
PANTHERi | PTHR11956. PTHR11956. 1 hit. |
Pfami | View protein in Pfam PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. |
PRINTSi | PR01038. TRNASYNTHARG. |
SMARTi | View protein in SMART SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. |
SUPFAMi | SSF47323. SSF47323. 1 hit. SSF55190. SSF55190. 1 hit. |
TIGRFAMsi | TIGR00456. argS. 1 hit. |
PROSITEi | View protein in PROSITE PS00178. AA_TRNA_LIGASE_I. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q3A6K6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKQRLRQYIG EALQACFDQQ QLHSGTIPEI NLEVPAHAEH GDFSTNVAMA
60 70 80 90 100
MARAEKKAPR KIAETIVAAL GEGGGMWSRV EIAGPGFINF YLTPRCWFGV
110 120 130 140 150
LDEVVRRGDL FGRTHTGNGR KVQVEFVSAN PTGPLHIGHG RGAATGDAVA
160 170 180 190 200
AVLGAAGYEV QREYYINDAG NQMLTLGRSL LLRYRELLGE TIEFPTDCYQ
210 220 230 240 250
GVYVIDLARE VLESEGERLR DLPEEEALRF FANYGGDKIR AGIDEDLAAF
260 270 280 290 300
GVRFDNWYSE QSLYDRQEVE RGIALLKERG LTYEKDGAIW FRTTDYGDDK
310 320 330 340 350
DRVLIRSNGA TTYFASDVAY HKEKFERGFD TVIDVWGADH HGYVPRMKAV
360 370 380 390 400
LAGLDRNPED LQIILVQLVN LLRGGQQVAM STRSGEFVTL REVIDEVGRD
410 420 430 440 450
ACRFFFLMRR SDSQLDFDLD LAKKQSTENP VYYVQYAHAR VCSINRNAED
460 470 480 490 500
QGVAMPELGE VDFDCLTLED ELALTKLLSR YPEVVDGAAE HFEPHRVVFY
510 520 530 540 550
LQELAARFHS YYNKGRVLVD DPDVSRARLY LVNCVRTVLH NALVLLGVSA
PERM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000142 Genomic DNA. Translation: ABA88001.1. |
RefSeqi | WP_011340444.1. NC_007498.2. |
Genome annotation databases
EnsemblBacteriai | ABA88001; ABA88001; Pcar_0742. |
KEGGi | pca:Pcar_0742. |
Similar proteinsi
Entry informationi
Entry namei | SYR_PELCD | |
Accessioni | Q3A6K6Primary (citable) accession number: Q3A6K6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 27, 2006 |
Last sequence update: | November 22, 2005 | |
Last modified: | February 28, 2018 | |
This is version 80 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |