Q3A6K6 (SYR_PELCD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase
EC=6.1.1.19

Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	Pcar_0742

Organism

Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) [Complete proteome] [HAMAP]

Taxonomic identifier

338963 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfuromonadales › Pelobacteraceae › Pelobacter › Pelobacter carbinolicus

Protein attributes

Sequence length	554 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00123
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: UniProtKB-HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: UniProtKB-HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 554	554	Arginine--tRNA ligase HAMAP-Rule MF_00123		PRO_0000242062
Regions
	Motif	129 – 139	11	"HIGH" region HAMAP-Rule MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q3A6K6 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 117FE0BBF0269B23	FASTA	554	62,387
	10 20 30 40 50 60 MKQRLRQYIG EALQACFDQQ QLHSGTIPEI NLEVPAHAEH GDFSTNVAMA MARAEKKAPR 70 80 90 100 110 120 KIAETIVAAL GEGGGMWSRV EIAGPGFINF YLTPRCWFGV LDEVVRRGDL FGRTHTGNGR 130 140 150 160 170 180 KVQVEFVSAN PTGPLHIGHG RGAATGDAVA AVLGAAGYEV QREYYINDAG NQMLTLGRSL 190 200 210 220 230 240 LLRYRELLGE TIEFPTDCYQ GVYVIDLARE VLESEGERLR DLPEEEALRF FANYGGDKIR 250 260 270 280 290 300 AGIDEDLAAF GVRFDNWYSE QSLYDRQEVE RGIALLKERG LTYEKDGAIW FRTTDYGDDK 310 320 330 340 350 360 DRVLIRSNGA TTYFASDVAY HKEKFERGFD TVIDVWGADH HGYVPRMKAV LAGLDRNPED 370 380 390 400 410 420 LQIILVQLVN LLRGGQQVAM STRSGEFVTL REVIDEVGRD ACRFFFLMRR SDSQLDFDLD 430 440 450 460 470 480 LAKKQSTENP VYYVQYAHAR VCSINRNAED QGVAMPELGE VDFDCLTLED ELALTKLLSR 490 500 510 520 530 540 YPEVVDGAAE HFEPHRVVFY LQELAARFHS YYNKGRVLVD DPDVSRARLY LVNCVRTVLH 550 NALVLLGVSA PERM

References

[1]

"Complete sequence of Pelobacter carbinolicus DSM 2380." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 2380 / Gra Bd 1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000142 Genomic DNA. Translation: ABA88001.1.
RefSeq	YP_006716438.1. NC_007498.2.
3D structure databases
ProteinModelPortal	Q3A6K6.
ModBase	Search...
MobiDB	Search...
Protein-protein interaction databases
STRING	338963.Pcar_0742.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABA88001; ABA88001; Pcar_0742.
GeneID	3722948.
KEGG	pca:Pcar_0742.
PATRIC	22887484. VBIPelCar86875_0811.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HOG000247214.
KO	K01887.
OMA	IRNTIND.
OrthoDB	EOG6JB13C.
Enzyme and pathway databases
BioCyc	PCAR338963:GKDU-836-MONOMER.
Family and domain databases
Gene3D	1.10.730.10. 1 hit. 3.30.1360.70. 1 hit. 3.40.50.620. 1 hit.
HAMAP	MF_00123. Arg_tRNA_synth.
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
PANTHER	PTHR11956. PTHR11956. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF47323. SSF47323. 1 hit. SSF55190. SSF55190. 1 hit.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_PELCD

Accession

Primary (citable) accession number: Q3A6K6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	November 22, 2005
Last modified:	May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program