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Q3A6I7

- TRMB_PELCD

UniProt

Q3A6I7 - TRMB_PELCD

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (22 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

    Catalytic activityi

    S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei38 – 381S-adenosyl-L-methionineUniRule annotation
    Binding sitei63 – 631S-adenosyl-L-methionineUniRule annotation
    Binding sitei90 – 901S-adenosyl-L-methionineUniRule annotation
    Active sitei113 – 1131By similarity
    Binding sitei113 – 1131S-adenosyl-L-methionineUniRule annotation
    Binding sitei117 – 1171SubstrateUniRule annotation
    Binding sitei149 – 1491SubstrateUniRule annotation

    GO - Molecular functioni

    1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciPCAR338963:GKDU-857-MONOMER.
    UniPathwayiUPA00989.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
    Alternative name(s):
    tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
    tRNA(m7G46)-methyltransferaseUniRule annotation
    Gene namesi
    Name:trmBUniRule annotation
    Ordered Locus Names:Pcar_0761
    OrganismiPelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
    Taxonomic identifieri338963 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesPelobacteraceaePelobacter
    ProteomesiUP000002534: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 232232tRNA (guanine-N(7)-)-methyltransferasePRO_0000229181Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi338963.Pcar_0761.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3A6I7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0220.
    HOGENOMiHOG000134942.
    KOiK03439.
    OMAiEWIELHI.
    OrthoDBiEOG6K6VBC.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    HAMAPiMF_01057. tRNA_methyltr_TrmB.
    InterProiIPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view]
    PfamiPF02390. Methyltransf_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
    PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3A6I7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTQHMIEIKS PYFLREESLA SPADFAAVFG NRNPLVLEIG CGIGDFVTQL    50
    ASSAPERNYL AIDIYNKGCN KTCNRLEQAR LTNVRVMRIE ARYLLEQFLA 100
    TESLAAVYIN CPDPWPKKRH LKRRLVNERF LQTLLHYLQP GGELFFSSDV 150
    ADYAHAVTAH LNQIKGYENR LPVPVALDMA GYPLSKYMRR FLAQGQSIHF 200
    IHHRRNPQHT CETAAPQPVH RGFRTAWSAN NG 232
    Length:232
    Mass (Da):26,466
    Last modified:November 22, 2005 - v1
    Checksum:i4A10A5DE1F337A22
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000142 Genomic DNA. Translation: ABA88020.1.
    RefSeqiYP_006716458.1. NC_007498.2.

    Genome annotation databases

    EnsemblBacteriaiABA88020; ABA88020; Pcar_0761.
    GeneIDi3723255.
    KEGGipca:Pcar_0761.
    PATRICi22887520. VBIPelCar86875_0828.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000142 Genomic DNA. Translation: ABA88020.1 .
    RefSeqi YP_006716458.1. NC_007498.2.

    3D structure databases

    ProteinModelPortali Q3A6I7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 338963.Pcar_0761.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABA88020 ; ABA88020 ; Pcar_0761 .
    GeneIDi 3723255.
    KEGGi pca:Pcar_0761.
    PATRICi 22887520. VBIPelCar86875_0828.

    Phylogenomic databases

    eggNOGi COG0220.
    HOGENOMi HOG000134942.
    KOi K03439.
    OMAi EWIELHI.
    OrthoDBi EOG6K6VBC.

    Enzyme and pathway databases

    UniPathwayi UPA00989 .
    BioCyci PCAR338963:GKDU-857-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    HAMAPi MF_01057. tRNA_methyltr_TrmB.
    InterProi IPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view ]
    Pfami PF02390. Methyltransf_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
    PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Pelobacter carbinolicus DSM 2380."
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
      Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 2380 / Gra Bd 1.

    Entry informationi

    Entry nameiTRMB_PELCD
    AccessioniPrimary (citable) accession number: Q3A6I7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3