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Protein

Putative fluoride ion transporter CrcB

Gene

crcB

Organism
Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Important for reducing fluoride concentration in the cell, thus reducing its toxicity.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciPCAR338963:GKDU-1109-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative fluoride ion transporter CrcBUniRule annotation
Gene namesi
Name:crcBUniRule annotation
Ordered Locus Names:Pcar_0981
OrganismiPelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1)
Taxonomic identifieri338963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesDesulfuromonadaceaePelobacter
Proteomesi
  • UP000002534 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei4 – 2421HelicalUniRule annotationAdd
BLAST
Transmembranei31 – 5121HelicalUniRule annotationAdd
BLAST
Transmembranei64 – 8320HelicalUniRule annotationAdd
BLAST
Transmembranei100 – 12021HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 123123Putative fluoride ion transporter CrcBPRO_0000252907Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi338963.Pcar_0981.

Family & Domainsi

Sequence similaritiesi

Belongs to the CrcB (TC 9.B.71) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105WMR. Bacteria.
COG0239. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiRFAITIG.
OrthoDBiPOG091H017F.

Family and domain databases

HAMAPiMF_00454. CrcB. 1 hit.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00494. crcB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3A5X3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLVYIAIFG ALGCLSRFMV SGWVYALIGR ALPYGTLAVN VIGSLLLGLL
60 70 80 90 100
MEGGLRSAAL PADIRMGITT GFMGGFTTFS TFSYETVRLL EDGSMVAAGA
110 120
NILLNVTVSV VFAGLGIFLA RQL
Length:123
Mass (Da):12,939
Last modified:November 22, 2005 - v1
Checksum:i4A524AEE76FFF677
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000142 Genomic DNA. Translation: ABA88234.1.
RefSeqiWP_011340701.1. NC_007498.2.

Genome annotation databases

EnsemblBacteriaiABA88234; ABA88234; Pcar_0981.
KEGGipca:Pcar_0981.
PATRICi22888034. VBIPelCar86875_1092.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000142 Genomic DNA. Translation: ABA88234.1.
RefSeqiWP_011340701.1. NC_007498.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi338963.Pcar_0981.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA88234; ABA88234; Pcar_0981.
KEGGipca:Pcar_0981.
PATRICi22888034. VBIPelCar86875_1092.

Phylogenomic databases

eggNOGiENOG4105WMR. Bacteria.
COG0239. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiRFAITIG.
OrthoDBiPOG091H017F.

Enzyme and pathway databases

BioCyciPCAR338963:GKDU-1109-MONOMER.

Family and domain databases

HAMAPiMF_00454. CrcB. 1 hit.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00494. crcB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCRCB_PELCD
AccessioniPrimary (citable) accession number: Q3A5X3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: November 22, 2005
Last modified: September 7, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.