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Q3A553 (Q3A553_PELCD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387 EMBL ABA88504.1
Ordered Locus Names:Pcar_1255
OrganismPelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) [Complete proteome] [HAMAP] EMBL ABA88504.1
Taxonomic identifier338963 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Pelobacteraceae › Pelobacter

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387 SAAS SAAS010137.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
Q3A553 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: C291A36B6D11E699

FASTA25627,769
        10         20         30         40         50         60 
MIHATAIIHD GARIEDGVEI GPYAVIGPHV SIAAGTSVGA HAVIEGWTDI GRDNRIFQFT 

        70         80         90        100        110        120 
SIGADPQDLK FHGEQSSLRI GDRNTIREFV TMHRGTEDGG LETVVGDDNL FMAYTHVAHD 

       130        140        150        160        170        180 
CIIGNRVILA NGATLGGHVR VDDWAILGGL SAIHQFTRVG CHAMISGGSM VTQDIAPYII 

       190        200        210        220        230        240 
AQGDRAKAAG INLVGLKRRG FSDEILRDIK QAYKLMFRSN LRQEQALDRI SAEISDAPEI 

       250 
KAFVDFIRTS ERGVAR

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References

[1]"Complete sequence of Pelobacter carbinolicus DSM 2380."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000142 Genomic DNA. Translation: ABA88504.1.
RefSeqYP_356674.1. NC_007498.2.

3D structure databases

ProteinModelPortalQ3A553.
SMRQ3A553. Positions 1-256.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3A553.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3723635.
GenomeReviewsGene locus Pcar_1255 in contig CP000142_GR.
KEGGpca:Pcar_1255.
NMPDRfig|338963.3.peg.1770.
PATRIC22888624. VBIPelCar86875_1385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1043.
HOGENOMHBG659295.
OMAREFCTFN.
PhylomeDBQ3A553.
ProtClustDBPRK05289.

Enzyme and pathway databases

BioCycPCAR338963:PCAR_1255-MONOMER.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 3 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3A553_PELCD
AccessionPrimary (citable) accession number: Q3A553
Entry history
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: December 14, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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