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Q3A515

- PUR5_PELCD

UniProt

Q3A515 - PUR5_PELCD

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene
purM, Pcar_1293
Organism
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPCAR338963:GKDU-1435-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:Pcar_1293
OrganismiPelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Taxonomic identifieri338963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesPelobacteraceaePelobacter
ProteomesiUP000002534: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 350350Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotationPRO_0000258377Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi338963.Pcar_1293.

Structurei

3D structure databases

ProteinModelPortaliQ3A515.
SMRiQ3A515. Positions 17-338.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229091.
KOiK01933.
OMAiVIGKIEH.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3A515-1 [UniParc]FASTAAdd to Basket

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MSDQKKMTYK DAGVDIDAGN RFVQLIKPLV KATSRPEVLT DIGGFGGLFS    50
LHADKYKKPT LVASTDGVGT KLKLAFMMDK HDTVGIDLVA MCVNDIVVQG 100
AEPLFFLDYM ATGKLTPEKA QDVVKGISEG CIQAGCALIG GETAEMPGFY 150
GEGEYDLAGF TVGIVDNTSI IDGSGITVGD RLIGLASSGL HSNGYSLARK 200
VLFEHLGLNA DSKVEELDLS VGEELLKPTR IYVKTILNLL RDFQIKGMAH 250
ITGGGLVENV PRMMPKNCQA IIHKDSWPKP PIFELLRKAG NIEEEEMYRT 300
LNYGIGMVLV VPETEAEEIM VRLSGLKEDA FIIGEIAKSA EEGEPTVTLI 350
Length:350
Mass (Da):37,843
Last modified:November 22, 2005 - v1
Checksum:iE39FB5D16F4971B3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000142 Genomic DNA. Translation: ABA88542.1.
RefSeqiWP_011341017.1. NC_007498.2.
YP_006717011.1. NC_007498.2.

Genome annotation databases

EnsemblBacteriaiABA88542; ABA88542; Pcar_1293.
GeneIDi3723595.
KEGGipca:Pcar_1293.
PATRICi22888702. VBIPelCar86875_1424.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000142 Genomic DNA. Translation: ABA88542.1 .
RefSeqi WP_011341017.1. NC_007498.2.
YP_006717011.1. NC_007498.2.

3D structure databases

ProteinModelPortali Q3A515.
SMRi Q3A515. Positions 17-338.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 338963.Pcar_1293.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA88542 ; ABA88542 ; Pcar_1293 .
GeneIDi 3723595.
KEGGi pca:Pcar_1293.
PATRICi 22888702. VBIPelCar86875_1424.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229091.
KOi K01933.
OMAi VIGKIEH.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci PCAR338963:GKDU-1435-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Pelobacter carbinolicus DSM 2380."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 2380 / Gra Bd 1.

Entry informationi

Entry nameiPUR5_PELCD
AccessioniPrimary (citable) accession number: Q3A515
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 22, 2005
Last modified: September 3, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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