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Q3A372 (KDSA_PELCD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
2-dehydro-3-deoxyphosphooctonate aldolase

EC=2.5.1.55
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase
KDO-8-phosphate synthase
Short name=KDO 8-P synthase
Short name=KDOPS
Phospho-2-dehydro-3-deoxyoctonate aldolase
Gene names
Name:kdsA
Ordered Locus Names:Pcar_1944
OrganismPelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) [Complete proteome] [HAMAP]
Taxonomic identifier338963 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesPelobacteraceaePelobacter

Protein attributes

Sequence length277 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP-Rule MF_00056

Pathway

Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP-Rule MF_00056

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP-Rule MF_00056

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00056.

Sequence similarities

Belongs to the KdsA family.

Ontologies

Keywords
   Biological processLipopolysaccharide biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processketo-3-deoxy-D-manno-octulosonic acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function3-deoxy-8-phosphooctulonate synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2772772-dehydro-3-deoxyphosphooctonate aldolase HAMAP-Rule MF_00056
PRO_0000304465

Sequences

Sequence LengthMass (Da)Tools
Q3A372 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 234E10EFE1AFBEF2

FASTA27729,354
        10         20         30         40         50         60 
MPDTLKVADV TFGGNHPVAL IAGPCVMENE AHTLAIARQL LEVKNELGVG VVFKASFDKA 

        70         80         90        100        110        120 
NRTSVSAYRG PGLESGLRIL DKVRQQTGLP IVSDIHDVSQ VEAAAEVLDI LQIPAFLCRQ 

       130        140        150        160        170        180 
TDLLLAAGRS GKVVNIKKGQ FLAPWDMANA VAKVASTGND RILLTERGTS FGYNNLVVDM 

       190        200        210        220        230        240 
RSLAVMRELG CPVVFDATHA VQLPGGAGTS SGGQRQFVAA LSRAAVAVGV DGLFWEVHPD 

       250        260        270 
PDRALCDGAN SLPLDQVKKT LKEMMAIDAI VKGNTES 

« Hide

References

[1]"Complete sequence of Pelobacter carbinolicus DSM 2380."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 2380 / Gra Bd 1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000142 Genomic DNA. Translation: ABA89185.1.
RefSeqYP_006717688.1. NC_007498.2.

3D structure databases

ProteinModelPortalQ3A372.
SMRQ3A372. Positions 17-276.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING338963.Pcar_1944.

Proteomic databases

PRIDEQ3A372.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA89185; ABA89185; Pcar_1944.
GeneID3724634.
KEGGpca:Pcar_1944.
PATRIC22890102. VBIPelCar86875_2103.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2877.
HOGENOMHOG000023021.
KOK01627.
OMADNFFLLA.
OrthoDBEOG680X4R.

Enzyme and pathway databases

BioCycPCAR338963:GKDU-2153-MONOMER.
UniPathwayUPA00030.
UPA00357; UER00474.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00056. KDO8P_synth.
InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
PANTHERPTHR21057:SF2. PTHR21057:SF2. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR01362. KDO8P_synth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKDSA_PELCD
AccessionPrimary (citable) accession number: Q3A372
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: November 22, 2005
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways