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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei351 – 3511Proton donorUniRule annotation
Active sitei382 – 3821UniRule annotation
Active sitei510 – 5101UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPCAR338963:GKDU-2612-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Pcar_2367
OrganismiPelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Taxonomic identifieri338963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesPelobacteraceaePelobacter
ProteomesiUP000002534: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 548548Glucose-6-phosphate isomerasePRO_0000230923Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi338963.Pcar_2367.

Structurei

3D structure databases

ProteinModelPortaliQ3A201.
SMRiQ3A201. Positions 2-543.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3A201-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLTDTQAWQH LQEHYRKISP LHMRDLFTQD SERFQRFSLS LEDLLFDYSK
60 70 80 90 100
NRINDQTVKL LCDLARERGL EDNIARMFAG EPINCSEQRP ALHVALRNRS
110 120 130 140 150
GRAIHVDGED VMPRVNAVLA QMRRFVEQVH SGAWRGYTGE PIRDVVNIGI
160 170 180 190 200
GGSDLGPRMV MEALTPYHHP GIRVHFVSNI DPAELLDTLK DLQPETTLFL
210 220 230 240 250
IASKTFGTQE TLANAHAARD WFMRAAQGAE HVARHFVAIS SHRQRVQQFG
260 270 280 290 300
IDPDNMFTFW DWVGGRYSLW SAIGLSIALG VGMDRFEELL AGAHAMDEHF
310 320 330 340 350
RSAPLEKNLP VIMGLLGVWY INLFGTASQA IVPYAQHLKS LPTYLQQADM
360 370 380 390 400
ESNGKGTTCD GDSVSFDTGP VVWGEPGTNG QHAFFQLLHQ GTRLIPVDFL
410 420 430 440 450
VPVRSHYSLA ENHDILVANC LAQSEALMRG RTEAEAVQQM QQQGLDDATV
460 470 480 490 500
LRLAPHRGFP GNRPSNLLMF DRLTPRTLGM LLALYEHKIY VQGALWGINS
510 520 530 540
FDQWGVELGK QLAGAILTEL REEDPTQGHD ASTAALIRRV WGKQVLPV
Length:548
Mass (Da):61,479
Last modified:April 4, 2006 - v2
Checksum:i778BEF7C6CF9CC32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000142 Genomic DNA. Translation: ABA89606.2.
RefSeqiYP_006718127.1. NC_007498.2.

Genome annotation databases

EnsemblBacteriaiABA89606; ABA89606; Pcar_2367.
GeneIDi3725069.
KEGGipca:Pcar_2367.
PATRICi22891032. VBIPelCar86875_2556.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000142 Genomic DNA. Translation: ABA89606.2.
RefSeqiYP_006718127.1. NC_007498.2.

3D structure databases

ProteinModelPortaliQ3A201.
SMRiQ3A201. Positions 2-543.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi338963.Pcar_2367.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA89606; ABA89606; Pcar_2367.
GeneIDi3725069.
KEGGipca:Pcar_2367.
PATRICi22891032. VBIPelCar86875_2556.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciPCAR338963:GKDU-2612-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Pelobacter carbinolicus DSM 2380."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 2380 / Gra Bd 1.

Entry informationi

Entry nameiG6PI_PELCD
AccessioniPrimary (citable) accession number: Q3A201
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: February 4, 2015
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.