Q3A1K1 (Q3A1K1_PELCD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ketol-acid reductoisomerase EMBL ABA89756.1
EC=1.1.1.86 EMBL ABA89756.1

Gene names

Name:	ilvC EMBL ABA89756.1
Ordered Locus Names:	Pcar_2518

Organism

Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) [Complete proteome] [HAMAP] EMBL ABA89756.1

Taxonomic identifier

338963 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Pelobacteraceae › Pelobacter

Protein attributes

Sequence length	490 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP+ = (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH. SAAS SAAS014359 (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH. SAAS SAAS014359
Pathway	Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4. SAAS SAAS014359 Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4. SAAS SAAS014359

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Branched-chain amino acid biosynthesis SAAS SAAS014359
Ligand	NADP SAAS SAAS014359
Molecular function	Isomerase EMBL ABA89756.1 Oxidoreductase SAAS SAAS014359 EMBL ABA89756.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	branched chain family amino acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW ketol-acid reductoisomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3A1K1 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 6CA163D3B6ED66EB	FASTA	490	53,788
	10 20 30 40 50 60 MGQNYFNSLP FRRQLQELGT CRFMDASEFA NGCEYAKGKK IVIVGCGAQG LNQGLNMRDS 70 80 90 100 110 120 GLDVSYTLRK GAIEEKRQSY LNATENGFAV GTYEEMLPTA DIVMNLAPDK QHTDVVNTVV 130 140 150 160 170 180 PLMKQGAVFS YAHGFNIVEE GTQIRKDLTV IMVAPKCPGS EVREEYKRGF GVPTLIAVHG 190 200 210 220 230 240 ENDPNGDGLE IAKALCSAQG GDRAGVLESS FVAEVKSDLM GEQTILCGML QAGALLCFDK 250 260 270 280 290 300 MTQNGIDAPY AVKLIQYGWE TITEALKHGG ITNMMDRLSN PAKLVAFGVA EELKEIMRPL 310 320 330 340 350 360 FEKHMDDILS GEFSSTMMED WANDDVKLLT WREETGKTAF EQTEGAGDIS EQEYFDKAIL 370 380 390 400 410 420 MVAMVKAGVE LAFEVMVSAG IEPESAYYES LHETPLIANT IARKKLYEMN RVISDTAEYG 430 440 450 460 470 480 CYLFSHACVP LLQDFMEKVG TDLIGKGLDA KDNSVDNSTL VSVNAEIRSH LIEEVGEELR 490 AAMQGMKAIV

References

[1]

"Complete sequence of Pelobacter carbinolicus DSM 2380." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000142 Genomic DNA. Translation: ABA89756.1.
RefSeq	YP_357926.1. NC_007498.2.
3D structure databases
ProteinModelPortal	Q3A1K1.
SMR	Q3A1K1. Positions 4-489.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3A1K1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3725220.
GenomeReviews	Gene locus Pcar_2518 in contig CP000142_GR.
KEGG	pca:Pcar_2518.
NMPDR	fig|338963.3.peg.2494.
PATRIC	22891368. VBIPelCar86875_2724.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0059.
HOGENOM	HBG297205.
OMA	EKHMDDI.
PhylomeDB	Q3A1K1.
ProtClustDB	PRK05225.
Enzyme and pathway databases
BioCyc	PCAR338963:PCAR_2518-MONOMER.
Family and domain databases
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR013023. AcH_isomrdctse. IPR000506. AcH_isomrdctse_C. IPR013328. DH_multihelical. IPR013116. IlvN. IPR014359. KetolA_reductoisomerase_bac. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00053.
PANTHER	PTHR21371. AcH_isomrdctse. 1 hit. PTHR21371:SF2. PTHR21371:SF2. 1 hit.
Pfam	PF01450. IlvC. 2 hits. PF07991. IlvN. 1 hit. [Graphical view]
PIRSF	PIRSF000116. IlvC_gammaproteo. 1 hit.
SUPFAM	SSF48179. 6DGDH_C_like. 2 hits.
TIGRFAMs	TIGR00465. IlvC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3A1K1_PELCD

Accession

Primary (citable) accession number: Q3A1K1

Entry history

Integrated into UniProtKB/TrEMBL:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)