Q39ZS0 (Q39ZS0_GEOMG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA gyrase subunit B RuleBase RU003363 HAMAP MF_01898
EC=5.99.1.3 RuleBase RU003363 HAMAP MF_01898

Gene names

Name:	gyrB HAMAP MF_01898
Ordered Locus Names:	Gmet_0004

Organism

Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) [Complete proteome] [HAMAP]

Taxonomic identifier

269799 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length	795 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363 HAMAP MF_01898
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. RuleBase RU003363 SAAS SAAS002288 HAMAP MF_01898
Subunit structure	Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898
Subcellular location	Cytoplasm By similarity HAMAP MF_01898.
Sequence similarities	Belongs to the type II topoisomerase family. HAMAP MF_01898 RuleBase RU000380 Contains 1 Toprim domain. SAAS SAAS002288 HAMAP MF_01898

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_01898
Ligand	ATP-binding SAAS SAAS002288 HAMAP MF_01898 RuleBase RU000380 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 HAMAP MF_01898 RuleBase RU000380
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro DNA-dependent DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q39ZS0 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: E7E8AD600D06AAEF	FASTA	795	88,597
	10 20 30 40 50 60 MADELNNDYG ADKIKVLEGL EAVRKRPAMY IGSTASQGLH HLVYEIVDNS IDEALAGYCN 70 80 90 100 110 120 EVNVTIHLDG SITVVDNGRG IPTEMHPTEG KPAAEVALTV LHAGGKFDNT SYKVSGGLHG 130 140 150 160 170 180 VGVSVVNALS KKLELGIRRD GKVFQQSYAY GAPLTPLEIV GETKKRGTRI TFLPDDTIFE 190 200 210 220 230 240 TTEFSFDILS QRLRELAFLN AGVRITISDE REEGKHHDFH YEGGIVSFVE YLNRNRTVLH 250 260 270 280 290 300 PKPVYFRGER AGIDMEIAIQ YNDSYDEKVF TFANNINTHE GGTHLVGFRA ALTRSMNSYA 310 320 330 340 350 360 AANELTKKEK VSISGEDLRE GLTAVISVKI PQPQFEGQTK TKLGNSEVKG FVESLMNEQL 370 380 390 400 410 420 AVFLEENPKI AKDIIGKSIE AARAREAARK ARELTRRKSA LDISSLPGKL ADCQERDPAL 430 440 450 460 470 480 CELYLVEGDS AGGSAKQGRD RKFQAILPLK GKILNVEKAR FDKMLSSQEI GTLITALGTS 490 500 510 520 530 540 IGKEDFDVAK LRYHRIIVMT DADVDGSHIL TLLLTFFFRQ MPEVVERGHL YIAQPPLYKV 550 560 570 580 590 600 KRGRKELYLR NEAAMQAYLL EEGTEDMVLF LENGEKTYTG KQIIPILKQL VEYRTILDKV 610 620 630 640 650 660 VRKGINEELI RVFLRLGVKA GIEDMEQLVP YLANISRVYE GGDSSPLDDG RAIVRLGNLR 670 680 690 700 710 720 IALDQHTLDI IGSYEYGLLA ESFRKVREMF GDGRAVVSSE GKELFATAIG LDLLSFFMDS 730 740 750 760 770 780 AKKGLSIQRY KGLGEMNPDQ LWETTMEPTN RTLLQVKIED AIEADTIFTI LMGDQVEPRR 790 DFIEKNALNV SNLDI

References

[1]

"Complete sequence of Geobacter metallireducens GS-15." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GS-15 / ATCC 53774 / DSM 7210.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000148 Genomic DNA. Translation: ABB30254.1.
RefSeq	YP_382979.1. NC_007517.1.
3D structure databases
ProteinModelPortal	Q39ZS0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q39ZS0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3739906.
GenomeReviews	Gene locus Gmet_0004 in contig CP000148_GR.
KEGG	gme:Gmet_0004.
NMPDR	fig|269799.3.peg.68.
PATRIC	21999138. VBIGeoMet55070_0017.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0187.
HOGENOM	HBG304889.
OMA	DCSSRDP.
PhylomeDB	Q39ZS0.
ProtClustDB	PRK14939.
Family and domain databases
HAMAP	MF_01898. GyrB. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR011557. GyrB. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KO	K02470.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01059. GyrB. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q39ZS0_GEOMG

Accession

Primary (citable) accession number: Q39ZS0

Entry history

Integrated into UniProtKB/TrEMBL:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)