ID   Q39WQ6_GEOMG            Unreviewed;       587 AA.
AC   Q39WQ6;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 96.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer, class 36H, Cache_2 domain-containing {ECO:0000313|EMBL:ABB31318.1};
GN   Name=mcp36H {ECO:0000313|EMBL:ABB31318.1};
GN   OrderedLocusNames=Gmet_1078 {ECO:0000313|EMBL:ABB31318.1};
OS   Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15).
OC   Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=269799 {ECO:0000313|EMBL:ABB31318.1, ECO:0000313|Proteomes:UP000007073};
RN   [1] {ECO:0000313|EMBL:ABB31318.1, ECO:0000313|Proteomes:UP000007073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53774 / DSM 7210 / GS-15
RC   {ECO:0000313|Proteomes:UP000007073};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Geobacter metallireducens GS-15.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABB31318.1, ECO:0000313|Proteomes:UP000007073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53774 / DSM 7210 / GS-15
RC   {ECO:0000313|Proteomes:UP000007073};
RX   PubMed=19473543; DOI=10.1186/1471-2180-9-109;
RA   Aklujkar M., Krushkal J., DiBartolo G., Lapidus A., Land M.L., Lovley D.R.;
RT   "The genome sequence of Geobacter metallireducens: features of metabolism,
RT   physiology and regulation common and dissimilar to Geobacter
RT   sulfurreducens.";
RL   BMC Microbiol. 9:109-109(2009).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000148; ABB31318.1; -; Genomic_DNA.
DR   RefSeq; WP_004513734.1; NC_007517.1.
DR   AlphaFoldDB; Q39WQ6; -.
DR   STRING; 269799.Gmet_1078; -.
DR   KEGG; gme:Gmet_1078; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_21_7; -.
DR   Proteomes; UP000007073; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR033480; sCache_2.
DR   PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF17200; sCache_2; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM01049; Cache_2; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007073};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        196..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          216..268
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          273..502
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          520..587
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          292..329
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          480..511
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        563..587
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   587 AA;  63050 MW;  DED6AEB1733C6159 CRC64;
     MKIKAFKDWK ILSKILAISV ATIVLIVSGI MFYVLPLVEK KLMAEKKDMV GSTVDTVVTL
     IGGYQEKVKS GELTEAEARK RAIDNIRKLR YDGNEYFWIN TVEPVMVMHP IKPELEGKKL
     DDLKDPTGKA FFVEMAKVAR EQGKGEVEYQ WPKPGATAPS PKISHVQLVK EWGWVVGSGI
     YVDDVQKEVM TMKIQIIVAT LICALVIFTF AYFVARRIRM ALGEAITASE HIAAGDLTAA
     IEASSEDETG QLLRSLREMN DSLSHIVAEV RTGADSIASA TEQISAGNAD LSQRTEEQAS
     ALEETASSME ELTSTVKQNA DNAQQANKLA VTASEVAERG GEVIGRVVNT MGAITDSSRK
     ISDIIGVIDG IAFQTNILAL NAAVEAARAG EQGRGFAVVA GEVRNLAQRS AAAAKEIKSL
     IEDSVAKVED GSRLVEEAGE TTREIVTSIK RVADIMAEIS AASIEQSSGI EQVNTAITQM
     DDVTQQNAAL VEEAAAAAEA LEDQARSMVS TVSRFKLADG GRADTGAAPK TERKPAARVA
     PSARNTPAAK AAPKAKAANG YHKPAAPEHH EAELPKAVGY DDDWKEF
//