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Protein

Ribonuclease Y

Gene

rny

Organism
Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Endoribonuclease that initiates mRNA decay.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciGMET269799:GHNY-1190-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease YUniRule annotation (EC:3.1.-.-UniRule annotation)
Short name:
RNase YUniRule annotation
Gene namesi
Name:rnyUniRule annotation
Ordered Locus Names:Gmet_1180
OrganismiGeobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Taxonomic identifieri269799 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000007073 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei3 – 2321HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 520520Ribonuclease YPRO_0000344881Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi269799.Gmet_1180.

Structurei

3D structure databases

ProteinModelPortaliQ39WF6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini210 – 27364KHUniRule annotationAdd
BLAST
Domaini336 – 42792HDUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the RNase Y family.UniRule annotation
Contains 1 HD domain.UniRule annotation
Contains 1 KH domain.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E4Y. Bacteria.
COG1418. LUCA.
HOGENOMiHOG000221256.
KOiK18682.
OMAiYYARGQA.
OrthoDBiEOG6QCD98.

Family and domain databases

Gene3Di1.10.3210.10. 1 hit.
3.30.1370.10. 1 hit.
HAMAPiMF_00335. RNase_Y.
InterProiIPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR006675. HDIG_dom.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR017705. Ribonuclease_Y.
IPR022711. RNase_Y_N.
[Graphical view]
PfamiPF12072. DUF3552. 1 hit.
PF01966. HD. 1 hit.
PF00013. KH_1. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
SM00322. KH. 1 hit.
[Graphical view]
SUPFAMiSSF54791. SSF54791. 1 hit.
TIGRFAMsiTIGR00277. HDIG. 1 hit.
TIGR03319. RNase_Y. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q39WF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIEIAIVLI LAAAGLGYFV GNMLRKRISD TLVSKAEELA SKIVDDAKRE
60 70 80 90 100
AETITKEAEL KAKDEVFQAK AEAERDAKEK RKDLQALEKR LQQKEENLDK
110 120 130 140 150
KMNLFDQRDA DLTKKDQALL NREQGLVQKE ERLDGLIAEQ REKLESISGL
160 170 180 190 200
SSTEAKKILM DAMESEAKLD AAKRIKVIEE EARETADKKS KEIMALAIQR
210 220 230 240 250
YAGEYVAERS VSVVALPSDE MKGRIIGREG RNIRALEAAT GIDLIIDDTP
260 270 280 290 300
EAVILSGFNP VRREVAKIAL EKLITDGRIH PGRIEEVVAK AEEEVEQTIK
310 320 330 340 350
EAGDQAAFDL GVHGIHPEIL KLIGRLKYRT SYSQNVYQHS LEVAFLCGIM
360 370 380 390 400
ASELGINVKQ AKRAGLLHDL GKAVDHEVEG SHAVIGAELA RKYGESPKIV
410 420 430 440 450
HAIMAHHEDE KPNTVLAVLV QAADALSGAR PGARREMMET YVKRLDDLER
460 470 480 490 500
IATSFVGVNN SFAIQAGREI RVMVSSDEVT DERAVVLAKD IAKKIEAEMT
510 520
YPGQIKVNVI RETRAIEYAR
Length:520
Mass (Da):57,741
Last modified:November 22, 2005 - v1
Checksum:i9FFD92FF4B8D2827
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000148 Genomic DNA. Translation: ABB31418.1.
RefSeqiWP_004513446.1. NC_007517.1.

Genome annotation databases

EnsemblBacteriaiABB31418; ABB31418; Gmet_1180.
KEGGigme:Gmet_1180.
PATRICi22001552. VBIGeoMet55070_1216.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000148 Genomic DNA. Translation: ABB31418.1.
RefSeqiWP_004513446.1. NC_007517.1.

3D structure databases

ProteinModelPortaliQ39WF6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269799.Gmet_1180.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB31418; ABB31418; Gmet_1180.
KEGGigme:Gmet_1180.
PATRICi22001552. VBIGeoMet55070_1216.

Phylogenomic databases

eggNOGiENOG4105E4Y. Bacteria.
COG1418. LUCA.
HOGENOMiHOG000221256.
KOiK18682.
OMAiYYARGQA.
OrthoDBiEOG6QCD98.

Enzyme and pathway databases

BioCyciGMET269799:GHNY-1190-MONOMER.

Family and domain databases

Gene3Di1.10.3210.10. 1 hit.
3.30.1370.10. 1 hit.
HAMAPiMF_00335. RNase_Y.
InterProiIPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR006675. HDIG_dom.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR017705. Ribonuclease_Y.
IPR022711. RNase_Y_N.
[Graphical view]
PfamiPF12072. DUF3552. 1 hit.
PF01966. HD. 1 hit.
PF00013. KH_1. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
SM00322. KH. 1 hit.
[Graphical view]
SUPFAMiSSF54791. SSF54791. 1 hit.
TIGRFAMsiTIGR00277. HDIG. 1 hit.
TIGR03319. RNase_Y. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Geobacter metallireducens GS-15."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS-15 / ATCC 53774 / DSM 7210.

Entry informationi

Entry nameiRNY_GEOMG
AccessioniPrimary (citable) accession number: Q39WF6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: November 22, 2005
Last modified: November 11, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.