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Q39R75

- TRMB_GEOMG

UniProt

Q39R75 - TRMB_GEOMG

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Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371S-adenosyl-L-methionineUniRule annotation
Binding sitei62 – 621S-adenosyl-L-methionineUniRule annotation
Binding sitei89 – 891S-adenosyl-L-methionineUniRule annotation
Active sitei112 – 1121By similarity
Binding sitei112 – 1121S-adenosyl-L-methionineUniRule annotation
Binding sitei116 – 1161SubstrateUniRule annotation
Binding sitei148 – 1481SubstrateUniRule annotation

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciGMET269799:GHNY-3080-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
Gene namesi
Name:trmBUniRule annotation
Ordered Locus Names:Gmet_3034
OrganismiGeobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Taxonomic identifieri269799 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000007073: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 211211tRNA (guanine-N(7)-)-methyltransferasePRO_0000229165Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi269799.Gmet_3034.

Structurei

3D structure databases

ProteinModelPortaliQ39R75.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000134942.
KOiK03439.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q39R75-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQRMIEISSP FFLNPDELST PADWAAVFGN ANPLALEIGC GIGDFIARTA
60 70 80 90 100
ADNPGTNYIA IDFYNKGCDK TCRRLERLAI PNVRVVRDEA RKFIVERIPK
110 120 130 140 150
GSLCAVHINC PDPWPKMRHR KRRLVNREFA AFIREYLAPG GDFYFATDFD
160 170 180 190 200
DYGIDVAEFM PGVEGYANML APDRYRHELE GYHLSKYMMK FMAEGKRIYF
210
VHYRKTAEGA A
Length:211
Mass (Da):24,163
Last modified:May 29, 2007 - v2
Checksum:i9172E0A938036299
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000148 Genomic DNA. Translation: ABB33249.2.
RefSeqiWP_011366135.1. NC_007517.1.
YP_006721988.1. NC_007517.1.

Genome annotation databases

EnsemblBacteriaiABB33249; ABB33249; Gmet_3034.
GeneIDi3741230.
KEGGigme:Gmet_3034.
PATRICi22005318. VBIGeoMet55070_3065.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000148 Genomic DNA. Translation: ABB33249.2 .
RefSeqi WP_011366135.1. NC_007517.1.
YP_006721988.1. NC_007517.1.

3D structure databases

ProteinModelPortali Q39R75.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 269799.Gmet_3034.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABB33249 ; ABB33249 ; Gmet_3034 .
GeneIDi 3741230.
KEGGi gme:Gmet_3034.
PATRICi 22005318. VBIGeoMet55070_3065.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000134942.
KOi K03439.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci GMET269799:GHNY-3080-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Geobacter metallireducens GS-15."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS-15 / ATCC 53774 / DSM 7210.

Entry informationi

Entry nameiTRMB_GEOMG
AccessioniPrimary (citable) accession number: Q39R75
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: May 29, 2007
Last modified: November 26, 2014
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3