ID   Q39MD0_BURL3            Unreviewed;       498 AA.
AC   Q39MD0;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   24-JAN-2024, entry version 96.
DE   SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:ABB06386.1};
DE            EC=1.2.1.3 {ECO:0000313|EMBL:ABB06386.1};
GN   OrderedLocusNames=Bcep18194_C7342 {ECO:0000313|EMBL:ABB06386.1};
GN   ORFNames=BLA6863_01442 {ECO:0000313|EMBL:VWB33382.1};
OS   Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 /
OS   R18194 / 383).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=482957 {ECO:0000313|EMBL:ABB06386.1, ECO:0000313|Proteomes:UP000002705};
RN   [1] {ECO:0000313|Proteomes:UP000002705}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383
RC   {ECO:0000313|Proteomes:UP000002705};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 3 of Burkholderia sp. 383.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABB06386.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=383 {ECO:0000313|EMBL:ABB06386.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 3 of Burkholderia sp. 383.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:VWB33382.1, ECO:0000313|Proteomes:UP000494170}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 6863 {ECO:0000313|EMBL:VWB33382.1};
RA   Depoorter E.;
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000150; ABB06386.1; -; Genomic_DNA.
DR   EMBL; CABVPY010000007; VWB33382.1; -; Genomic_DNA.
DR   RefSeq; WP_011350029.1; NZ_CABVPY010000007.1.
DR   AlphaFoldDB; Q39MD0; -.
DR   GeneID; 45092721; -.
DR   KEGG; bur:Bcep18194_C7342; -.
DR   PATRIC; fig|482957.22.peg.7929; -.
DR   HOGENOM; CLU_005391_0_0_4; -.
DR   Proteomes; UP000002705; Chromosome 3.
DR   Proteomes; UP000494170; Unassembled WGS sequence.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          29..492
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        265
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   498 AA;  53479 MW;  81586E921D18B519 CRC64;
     MLSLVSHLDH LNVRPGRLFI DGQWLDWPDA RFDQLNPCTN EVMTSFADAG AQGVELAVAA
     ARKAFDEGPW PRMRAQDRKR LLQPIVERLY AAEEEIARLQ TLDNGIPYAF SRHSRVSAKS
     AADVFDHFLG WIDKINGDTL PIFSGASNMQ YMTFRDPVGV VAAVLPYNGP VLTFAMKVAP
     ALACGCTVIV KSSELTNLAV ARLAQIIADS DLPPGVFNFV TGGVETGSAL TSHAGVDKVT
     FTGSPAVGEK IMIASAPTMK RLSLELGGKS AALVFPDTRS VQTTAHALMG LCSTFLSGQV
     CSTPSRAVVH RSIMDEFLHH AQEQLQKVRF GDPFDAATTS APMISRRHQA RVLDYVESGR
     QQGATLLAGG RAPGGEFRNG NWVEPALFAN VSNDMTIAQE EIFGPVLSVI PFDTEEEAIR
     IANDSAYGLA GCVYTTDVSR AFRVARAVKS GAIGVNGFAS IPNAPFGGIK RSGTGREGGW
     STIEAFTELK TVNFNLDA
//