Reviewed,
UniProtKB/Swiss-Prot Q39J54 (HGD_BURS3)
Last modified
November 4, 2008.
Version 23.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Homogentisate 1,2-dioxygenase EC=1.13.11.5 Alternative name(s): Homogentisicase Homogentisate oxygenase Homogentisic acid oxidase | ||||
| Gene names |
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| Organism | Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 269483 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex |
Protein attributes
| Sequence length | 444 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Homogentisate + O(2) = 4-maleylacetoacetate. |
| Cofactor | Iron By similarity. |
| Pathway | |
| Sequence similarities | Belongs to the homogentisate dioxygenase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Phenylalanine catabolism Tyrosine catabolism |
| Ligand | Iron Metal-binding |
| Molecular function | Dioxygenase Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | L-phenylalanine catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW tyrosine catabolic processInferred from electronic annotation. Source: HAMAP |
| Molecular function | homogentisate 1,2-dioxygenase activity Inferred from electronic annotation. Source: HAMAP iron ion bindingInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Complete sequence of chromosome 1 of Burkholderia sp. 383." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000151 Genomic DNA. Translation: ABB07512.1. | |
| RefSeq | YP_368156.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3749098. |
| GenomeReviews | Gene locus Bcep18194_A3913 in contig CP000151_GR. |
| KEGG | bur:Bcep18194_A3913. |
| NMPDR | fig|269483.3.peg.4675. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q39J54. |
Enzyme and pathway databases | |
| BioCyc | BSP36773:BCEP18194_A3913-MON. |
Family and domain databases | |
| HAMAP | MF_00334. [Tree] |
| InterPro | IPR005708. Homogentis_dOase. [Graphical view] |
| PANTHER | PTHR11056. Homogentis_dOase. 1 hit. |
| Pfam | PF04209. HgmA. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01015. hmgA. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | HGD_BURS3 | ||||||||
| Accession | Primary (citable) accession number: Q39J54 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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