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Reviewed, UniProtKB/Swiss-Prot Q39IL2 (KGUA_BURS3)

Last modified November 3, 2009. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Guanylate kinase
    EC=2.7.4.8
Alternative name(s):
    GMP kinase
Gene names
Name: gmk
Ordered Locus Names: Bcep18194_A4107
OrganismBurkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) [Complete proteome] [HAMAP]
Taxonomic identifier269483 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity.

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP MF_00328

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

guanylate kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 227227Guanylate kinase HAMAP MF_00328
PRO_0000266297

Regions

Domain21 – 199179Guanylate kinase-like
Nucleotide binding28 – 358ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q39IL2-1 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 314ED4AA15B44915

FASTA22725,419
        10         20         30         40         50         60 
MTQSTHDGHA AHSLHGGVYP GNLFMVVAPS GAGKSTLVNA LLSKDSDICL SISYTTRKPR 

        70         80         90        100        110        120 
PGEQDGQHYH FTTVEDFRTR HAAHEFLESA EVHGNYYGTS RVWIEEQMKN GHDVLLEIDW 

       130        140        150        160        170        180 
QGALQVKKQF RNAVGIFILP PSLDALEERL KKRGQDEPKV ITRRLLAAGS EIAHAPEAEY 

       190        200        210        220 
VVINENFERA LAELECIVAA TRLRFASQYA RHTELFIELG IHLPHAE 

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia sp. 383."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000151 Genomic DNA. Translation: ABB07704.1.
RefSeqYP_368348.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ39IL2.

Genome annotation databases

GeneID3749295.
GenomeReviewsGene locus Bcep18194_A4107 in contig CP000151_GR.
KEGGbur:Bcep18194_A4107.
NMPDRfig|269483.3.peg.5115.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ39IL2.
OMAEWAEFAG.

Enzyme and pathway databases

BioCycBSP36773:BCEP18194_A4107-MON.

Family and domain databases

HAMAPMF_00328.
[Tree]
InterProIPR008144. Guanylate_kin.
IPR020590. Guanylate_kinase_CS.
IPR017665. Guanylate_kinase_sub.
IPR008145. Guanylt/Ca.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
TIGRFAMsTIGR03263. guanyl_kin. 1 hit.
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_BURS3
AccessionPrimary (citable) accession number: Q39IL2
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: November 22, 2005
Last modified: November 3, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents