Q39HM9 (GLMM_BURS3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Bcep18194_A4441

Organism

Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) [Complete proteome] [HAMAP]

Taxonomic identifier

269483 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	451 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP-Rule MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP-Rule MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP-Rule MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 451	451	Phosphoglucosamine mutase HAMAP-Rule MF_01554		PRO_0000301293
Sites
	Active site	107	1	Phosphoserine intermediate By similarity
	Metal binding	107	1	Magnesium; via phosphate group By similarity
	Metal binding	246	1	Magnesium By similarity
	Metal binding	248	1	Magnesium By similarity
	Metal binding	250	1	Magnesium By similarity
Amino acid modifications
	Modified residue	107	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q39HM9 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 21C5165323BA0691	FASTA	451	47,240
	10 20 30 40 50 60 MGRRYFGTDG IRGTVGEGPI TPDFVLRLGY AAGKVLASSA EVAAGSRPTV LIGKDTRVSG 70 80 90 100 110 120 YMLEAALEAG FSAAGVDVML AGPMPTPGVA YLTRALRLSA GVVISASHNP YHDNGIKFFS 130 140 150 160 170 180 ADGNKLPDDT EAAIEAWLDK PLECASSDGL GKARRLDDAA GRYIEFCKST FPAAFNLRGL 190 200 210 220 230 240 KLVIDCAHGA AYQIAPHVFH ELGADVIPIG VAPNGFNIND GVGATAPDAL VRAVRANHAD 250 260 270 280 290 300 LGIALDGDAD RLQVVDSTGR LYNGDELLYV LVKDRIATDG KVEGAVGTLM TNLAVEVALQ 310 320 330 340 350 360 REGVKFVRAA VGDRYVLEQL REHGWQLGAE GSGHILSLDR HSTGDGIVSA LLVLAALKRS 370 380 390 400 410 420 GQTLAQMLDG VTLFPQKLIN VRMKPGADWK GSTSIRAAID TAEAALAGSG RVLIRASGTE 430 440 450 PVLRVMVEAQ QAADAVRHAE TIADAVRAAT T

References

[1]

"Complete sequence of chromosome 1 of Burkholderia sp. 383." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 383.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000151 Genomic DNA. Translation: ABB08037.1.
RefSeq	YP_368681.1. NC_007510.1.
3D structure databases
ProteinModelPortal	Q39HM9.
ModBase	Search...
Protein-protein interaction databases
STRING	269483.Bcep18194_A4441.
Proteomic databases
PRIDE	Q39HM9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABB08037; ABB08037; Bcep18194_A4441.
GeneID	3749640.
KEGG	bur:Bcep18194_A4441.
PATRIC	19286260. VBIBurSp120713_2548.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HOG000268678.
KO	K03431.
OMA	TLMSNMS.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	BSP269483:GHLS-1296-MONOMER.
Family and domain databases
Gene3D	3.40.120.10. 3 hits.
HAMAP	MF_01554_B. GlmM_B.
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BURS3

Accession

Primary (citable) accession number: Q39HM9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	November 22, 2005
Last modified:	May 29, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program