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Q39GX3

- LFTR_BURS3

UniProt

Q39GX3 - LFTR_BURS3

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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene
aat, Bcep18194_A4698
Organism
Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194))
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciBSP269483:GHLS-1560-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase (EC:2.3.2.6)
Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase
Gene namesi
Name:aat
Ordered Locus Names:Bcep18194_A4698
OrganismiBurkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194))
Taxonomic identifieri482957 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000002705: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 254254Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotationPRO_0000258050Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi269483.Bcep18194_A4698.

Structurei

3D structure databases

ProteinModelPortaliQ39GX3.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiWSPDPRG.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

Q39GX3-1 [UniParc]FASTAAdd to Basket

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MVPWLGPDDP FPPIERALGP ATGAPGLLAA SADLLPSRLI DAYLRGIFPW    50
YSDGQPVLWW SPDPRMILVP AEFKVSPSLR KTLKRVLREP EWEVRVDHDF 100
PGVMRACAQA PRRGQRGTWI TAEIIDAYTS LYRSGNAHSI ETWHDGRRVG 150
GLYGVSFGRM FFGESMYADA TDASKIALAT LVAHLREQGL EMIDCQQNTS 200
HLASLGGREI ARKAFVAHVR SAVAEPPIPW QFDKRVLAAL TGRAEAAAPS 250
GIER 254
Length:254
Mass (Da):28,010
Last modified:November 22, 2005 - v1
Checksum:i675D4047823581D2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000151 Genomic DNA. Translation: ABB08293.1.
RefSeqiWP_011351854.1. NC_007510.1.
YP_368937.1. NC_007510.1.

Genome annotation databases

EnsemblBacteriaiABB08293; ABB08293; Bcep18194_A4698.
GeneIDi3749904.
KEGGibur:Bcep18194_A4698.
PATRICi19286809. VBIBurSp120713_2814.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000151 Genomic DNA. Translation: ABB08293.1 .
RefSeqi WP_011351854.1. NC_007510.1.
YP_368937.1. NC_007510.1.

3D structure databases

ProteinModelPortali Q39GX3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 269483.Bcep18194_A4698.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABB08293 ; ABB08293 ; Bcep18194_A4698 .
GeneIDi 3749904.
KEGGi bur:Bcep18194_A4698.
PATRICi 19286809. VBIBurSp120713_2814.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102325.
KOi K00684.
OMAi WSPDPRG.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci BSP269483:GHLS-1560-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia sp. 383."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 383.

Entry informationi

Entry nameiLFTR_BURS3
AccessioniPrimary (citable) accession number: Q39GX3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 22, 2005
Last modified: September 3, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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