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Q39FF4

- G6PI_BURS3

UniProt

Q39FF4 - G6PI_BURS3

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194))
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 2 (04 Apr 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei350 – 3501Proton donorUniRule annotation
    Active sitei381 – 3811UniRule annotation
    Active sitei503 – 5031UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciBSP269483:GHLS-2082-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:Bcep18194_A5218
    OrganismiBurkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194))
    Taxonomic identifieri482957 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
    ProteomesiUP000002705: Chromosome 1

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 540540Glucose-6-phosphate isomerasePRO_0000230914Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi269483.Bcep18194_A5218.

    Structurei

    3D structure databases

    ProteinModelPortaliQ39FF4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q39FF4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTLNSLPAWT ALQSHFEQIR HARLRDWFAP ENDHTPTRAE RFTIPGGGIA    50
    ADFSKNRIND DTLRLLVQLA RDAGVEARRD AMFAGEIVNP TEGRAALHTA 100
    LRATDPQAPF HAQISAERAK MATFARAVRS GTWTGYTGKR IRHVINIGIG 150
    GSDLGPKMVV HALHHVATPE ITTHFVSNVD GADLARVLEQ VDPEETLAII 200
    VSKTFTTLET MTNARSLRDW FVARGCPEDA LAKHFVGVSA NPAEVVKFGI 250
    AADNVFEMWD WVGGRYSLWS AVGLSIMIAI GPEQFDELLA GANDMDRHFR 300
    EAPLERNLPV LLGLIGIWYR NFFGSQSYLV APYSEALHYL PSYLQQLEME 350
    SNGKSARLDG TFVDYPTSAV TWGEPGTNGQ HAFFQMLHQG PTIVPIDFIA 400
    VLTPEHPLAS HHPKLLANCF AQSEALMLGR TLDEARKVAG PGKEALAPHL 450
    TFPGNRPTTT LLVDALTPRT LGALIALYEH KVLVQATVWD INPFDQWGVE 500
    LGKILGKVVE ADLSAESIDP AKHDSSTTAL IERARAALKR 540
    Length:540
    Mass (Da):59,313
    Last modified:April 4, 2006 - v2
    Checksum:i1F39546BC4690DCA
    GO

    Sequence cautioni

    The sequence ABB08812.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000151 Genomic DNA. Translation: ABB08812.1. Different initiation.
    RefSeqiWP_011352357.1. NC_007510.1.
    YP_369456.1. NC_007510.1.

    Genome annotation databases

    EnsemblBacteriaiABB08812; ABB08812; Bcep18194_A5218.
    GeneIDi3750427.
    KEGGibur:Bcep18194_A5218.
    PATRICi19287831. VBIBurSp120713_3319.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000151 Genomic DNA. Translation: ABB08812.1 . Different initiation.
    RefSeqi WP_011352357.1. NC_007510.1.
    YP_369456.1. NC_007510.1.

    3D structure databases

    ProteinModelPortali Q39FF4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 269483.Bcep18194_A5218.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB08812 ; ABB08812 ; Bcep18194_A5218 .
    GeneIDi 3750427.
    KEGGi bur:Bcep18194_A5218.
    PATRICi 19287831. VBIBurSp120713_3319.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci BSP269483:GHLS-2082-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 1 of Burkholderia sp. 383."
      US DOE Joint Genome Institute
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
      Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 383.

    Entry informationi

    Entry nameiG6PI_BURS3
    AccessioniPrimary (citable) accession number: Q39FF4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: April 4, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3