Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable chorismate pyruvate-lyase

Gene

ubiC

Organism
Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.UniRule annotation

Catalytic activityi

Chorismate = 4-hydroxybenzoate + pyruvate.UniRule annotation

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei73 – 731SubstrateUniRule annotation
Binding sitei111 – 1111Substrate; via amide nitrogenUniRule annotation
Binding sitei172 – 1721SubstrateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Ubiquinone biosynthesis

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

BioCyciBSP269483:GHLS-2569-MONOMER.
UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable chorismate pyruvate-lyaseUniRule annotation (EC:4.1.3.40UniRule annotation)
Short name:
CLUniRule annotation
Short name:
CPLUniRule annotation
Gene namesi
Name:ubiCUniRule annotation
Ordered Locus Names:Bcep18194_A5685
OrganismiBurkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383)
Taxonomic identifieri482957 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000002705 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198Probable chorismate pyruvate-lyasePRO_0000240541Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ39E37.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UbiC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000137785.
KOiK03181.
OMAiHGAPLMV.
OrthoDBiPOG091H047C.

Family and domain databases

Gene3Di3.40.1410.10. 1 hit.
HAMAPiMF_01632. UbiC. 1 hit.
InterProiIPR007440. Chorismate--pyruvate_lyase.
IPR028978. Chorismate_lyase_/UTRA_dom.
[Graphical view]
PfamiPF04345. Chor_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF64288. SSF64288. 1 hit.

Sequencei

Sequence statusi: Complete.

Q39E37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFDGGQAGW RETPRPGCTL DQRDWLTRGG SLTAHLARLG RVNVRVTREA
60 70 80 90 100
VDCPWFDEPD AVASAPRAPM WVREVILSVD GTPYVAAHSI APLAASKGVW
110 120 130 140 150
QAMRRLRTRP LAELLYSDPQ VERSALVSRR VIAGHPLYAL ATHALGGARA
160 170 180 190
PHSFAARRSV FQRHGKPLMV TECMLPALWR HLDAHGDGPR SGGPGGGA
Length:198
Mass (Da):21,549
Last modified:November 22, 2005 - v1
Checksum:i7FD06FDC55D9869E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000151 Genomic DNA. Translation: ABB09279.1.
RefSeqiWP_011352805.1. NC_007510.1.

Genome annotation databases

EnsemblBacteriaiABB09279; ABB09279; Bcep18194_A5685.
KEGGibur:Bcep18194_A5685.
PATRICi19288858. VBIBurSp120713_3811.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000151 Genomic DNA. Translation: ABB09279.1.
RefSeqiWP_011352805.1. NC_007510.1.

3D structure databases

ProteinModelPortaliQ39E37.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB09279; ABB09279; Bcep18194_A5685.
KEGGibur:Bcep18194_A5685.
PATRICi19288858. VBIBurSp120713_3811.

Phylogenomic databases

HOGENOMiHOG000137785.
KOiK03181.
OMAiHGAPLMV.
OrthoDBiPOG091H047C.

Enzyme and pathway databases

UniPathwayiUPA00232.
BioCyciBSP269483:GHLS-2569-MONOMER.

Family and domain databases

Gene3Di3.40.1410.10. 1 hit.
HAMAPiMF_01632. UbiC. 1 hit.
InterProiIPR007440. Chorismate--pyruvate_lyase.
IPR028978. Chorismate_lyase_/UTRA_dom.
[Graphical view]
PfamiPF04345. Chor_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF64288. SSF64288. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUBIC_BURL3
AccessioniPrimary (citable) accession number: Q39E37
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 22, 2005
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.