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Q39E37 (UBIC_BURS3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable chorismate--pyruvate lyase
Short name=CL
Short name=CPL
EC=4.1.3.40
Gene names
Name:ubiC
Ordered Locus Names:Bcep18194_A5685
OrganismBurkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) [Complete proteome] [HAMAP]
Taxonomic identifier269483 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632

Catalytic activity

Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632

Subcellular location

Cytoplasm By similarity HAMAP MF_01632.

Sequence similarities

Belongs to the ubiC family.

Ontologies

Keywords
   Biological processUbiquinone biosynthesis
   Cellular componentCytoplasm
   LigandPyruvate
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processubiquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionchorismate lyase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Probable chorismate--pyruvate lyase HAMAP MF_01632
PRO_0000240541

Sites

Binding site731Substrate By similarity
Binding site1111Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q39E37 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 7FD06FDC55D9869E

FASTA19821,549
        10         20         30         40         50         60 
MRFDGGQAGW RETPRPGCTL DQRDWLTRGG SLTAHLARLG RVNVRVTREA VDCPWFDEPD 

        70         80         90        100        110        120 
AVASAPRAPM WVREVILSVD GTPYVAAHSI APLAASKGVW QAMRRLRTRP LAELLYSDPQ 

       130        140        150        160        170        180 
VERSALVSRR VIAGHPLYAL ATHALGGARA PHSFAARRSV FQRHGKPLMV TECMLPALWR 

       190 
HLDAHGDGPR SGGPGGGA

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia sp. 383."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 383.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000151 Genomic DNA. Translation: ABB09279.1.
RefSeqYP_369923.1. NC_007510.1.

3D structure databases

ProteinModelPortalQ39E37.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ39E37.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3750913.
GenomeReviewsGene locus Bcep18194_A5685 in contig CP000151_GR.
KEGGbur:Bcep18194_A5685.
NMPDRfig|269483.3.peg.7025.
PATRIC19288858. VBIBurSp120713_3811.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3161.
HOGENOMHBG644467.
OMATREAVDC.
ProtClustDBCLSK920196.

Enzyme and pathway databases

BioCycBSP36773:BCEP18194_A5685-MONOMER.

Family and domain databases

HAMAPMF_01632. UbiC.
[Tree]
InterProIPR007440. Chorismate--pyruvate_lyase.
[Graphical view]
KOK03181.
PfamPF04345. Chor_lyase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBIC_BURS3
AccessionPrimary (citable) accession number: Q39E37
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 22, 2005
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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