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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei218 – 2181UniRule annotation
Active sitei660 – 6601UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBSP269483:GHLS-2639-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Bcep18194_A5753Imported
OrganismiBurkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383)Imported
Taxonomic identifieri482957 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000002705: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi269483.Bcep18194_A5753.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q39DW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSGSARTA RRNAALSSSD ASTDTVATAA NGRAKTATKP KDPIRQTKRT
60 70 80 90 100
AKAAGPAART AARTAAAPKS GTRTREDKDG PLFDDIRFLG RLLGDVVREQ
110 120 130 140 150
EGDTVFDVVE TIRQTAVKFR REDDSEAAQT LEKKLRKLTP EQTVSVVRAF
160 170 180 190 200
SYFSHLANIA EDRHHNRRRR IHALAGSASQ PGTVAYALEQ LKTTGNASKR
210 220 230 240 250
LLQRFFDDAL IVPVLTAHPT EVQRKSILDA QHDIARLLAE RDQELTGRER
260 270 280 290 300
QYNESMLRAR VTALWQTRML RDARLTVGDE IENALSYYRA TFLDELPALY
310 320 330 340 350
GDIEAALAEH GLSARVPAFF QMGSWIGGDR DGNPNVTAPT LEEAINRQAA
360 370 380 390 400
VILEHYLEQV HKLGAELSVS NLLVGANDAV KALAAASPDQ SPHRVDEPYR
410 420 430 440 450
RALIGIYTRL AASARVRLGE GTVPVRSAGR GAAPVRATPY ADSEAFVADL
460 470 480 490 500
KVLTASLDEH HGTSLAAPRL APLVRAAEVF GFHLASIDLR QSSDIHEAVV
510 520 530 540 550
AELFARAGVE ADYAALAEED KLRVLLAALA DPRPLRSPYF EYSALAQSEL
560 570 580 590 600
GVFEKAREVR AQFGARAVRN YIISHTETVS DLVEVLLLQK ETGLLDGALG
610 620 630 640 650
VPGGDAKNSL MVIPLFETIP DLRDAARIMR EYFALPGIDA LIAHQGAEQE
660 670 680 690 700
VMLGYSDSNK DGGFLTSNWE LYRAELALVD LFRDRKITLR LFHGRGGTVG
710 720 730 740 750
RGGGPTYQAI LSQPPGTVNG QIRLTEQGEV IASKFANPEI GRRNLETVVA
760 770 780 790 800
ATLEATLLPQ NNAPAQLPAF EAAMQTLSDS AMAAYRALVY ETPGFTDYFF
810 820 830 840 850
SSTPITEIAE LNIGSRPASR KLQDPKQRKI EDLRAIPWGF SWGQCRLLLT
860 870 880 890 900
GWYGFGSAVS AYLDGAQDDA ERTKRVALLK KMNKTWPFFA NLLSNMDMVL
910 920 930 940 950
AKTDLAVASR YAQLVSDRKL RKHVFERIVA EWERTSQALA EITGHEGRLA
960 970 980 990 1000
TNPLLARSIK NRFPYLDPLN HLQVELIKRH RAGDTNARLR RGIHLTINGI

AAGLRNTG
Length:1,008
Mass (Da):110,609
Last modified:November 22, 2005 - v1
Checksum:iE1B17BA931229DF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000151 Genomic DNA. Translation: ABB09347.1.
RefSeqiWP_011352872.1. NC_007510.1.
YP_369991.1. NC_007510.1.

Genome annotation databases

EnsemblBacteriaiABB09347; ABB09347; Bcep18194_A5753.
GeneIDi3750983.
KEGGibur:Bcep18194_A5753.
PATRICi19288990. VBIBurSp120713_3875.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000151 Genomic DNA. Translation: ABB09347.1.
RefSeqiWP_011352872.1. NC_007510.1.
YP_369991.1. NC_007510.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269483.Bcep18194_A5753.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB09347; ABB09347; Bcep18194_A5753.
GeneIDi3750983.
KEGGibur:Bcep18194_A5753.
PATRICi19288990. VBIBurSp120713_3875.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciBSP269483:GHLS-2639-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia sp. 383."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383Imported.

Entry informationi

Entry nameiQ39DW9_BURL3
AccessioniPrimary (citable) accession number: Q39DW9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: March 4, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.