ID   Q39DJ8_BURL3            Unreviewed;       192 AA.
AC   Q39DJ8;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   RecName: Full=Superoxide dismutase {ECO:0000256|ARBA:ARBA00012682, ECO:0000256|RuleBase:RU000414};
DE            EC=1.15.1.1 {ECO:0000256|ARBA:ARBA00012682, ECO:0000256|RuleBase:RU000414};
GN   OrderedLocusNames=Bcep18194_A5874 {ECO:0000313|EMBL:ABB09468.1};
GN   ORFNames=BLA14095_05001 {ECO:0000313|EMBL:VWC06055.1}, BLA18110_06082
GN   {ECO:0000313|EMBL:VWD30104.1}, BLA18112_02796
GN   {ECO:0000313|EMBL:VWC83266.1}, BLA23254_05985
GN   {ECO:0000313|EMBL:VWC24525.1}, BLA39750_07809
GN   {ECO:0000313|EMBL:VWD63933.1}, BLA50215_03071
GN   {ECO:0000313|EMBL:VWD08454.1}, BLA6860_01806
GN   {ECO:0000313|EMBL:VWB40519.1}, BLA6863_07785
GN   {ECO:0000313|EMBL:VWC50051.1}, BLA6992_05465
GN   {ECO:0000313|EMBL:VWM15041.1}, CVS37_15745
GN   {ECO:0000313|EMBL:AYQ39381.1}, GAK33_07085
GN   {ECO:0000313|EMBL:KAF1032284.1}, VL13_30375
GN   {ECO:0000313|EMBL:KML35678.1};
OS   Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 /
OS   R18194 / 383).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=482957 {ECO:0000313|EMBL:ABB09468.1, ECO:0000313|Proteomes:UP000002705};
RN   [1] {ECO:0000313|Proteomes:UP000002705}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383
RC   {ECO:0000313|Proteomes:UP000002705};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia sp. 383.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABB09468.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=383 {ECO:0000313|EMBL:ABB09468.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia sp. 383.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:KML35678.1, ECO:0000313|Proteomes:UP000036521}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LK27 {ECO:0000313|EMBL:KML35678.1,
RC   ECO:0000313|Proteomes:UP000036521};
RA   Chan X.Y.;
RT   "Draft genome of Burkholderia lata LK27.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:AYQ39381.1, ECO:0000313|Proteomes:UP000280305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A05 {ECO:0000313|EMBL:AYQ39381.1,
RC   ECO:0000313|Proteomes:UP000280305};
RA   Leong L.E.;
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|Proteomes:UP000494110, ECO:0000313|Proteomes:UP000494126}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 14095 {ECO:0000313|EMBL:VWC06055.1}, LMG 23254
RC   {ECO:0000313|EMBL:VWC24525.1}, LMG 6860t1
RC   {ECO:0000313|EMBL:VWB40519.1}, LMG 6863 {ECO:0000313|EMBL:VWC50051.1},
RC   LMG 6992 {ECO:0000313|EMBL:VWM15041.1,
RC   ECO:0000313|Proteomes:UP000494177}, R-18110
RC   {ECO:0000313|EMBL:VWD30104.1}, R-18112 {ECO:0000313|EMBL:VWC83266.1},
RC   R-39750 {ECO:0000313|EMBL:VWD63933.1}, and R-50215
RC   {ECO:0000313|EMBL:VWD08454.1};
RA   Depoorter E.;
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|Proteomes:UP000467522}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Waterworth S.C., Florez L.V., Rees E.R., Hertweck C., Kaltenpoth M.,
RA   Kwan J.C.;
RT   "Horizontal gene transfer to a defensive symbiont with a reduced genome
RT   amongst a multipartite beetle microbiome.";
RL   MBio 11:e02430-19(2020).
CC   -!- FUNCTION: Destroys radicals which are normally produced within the
CC       cells and which are toxic to biological systems.
CC       {ECO:0000256|RuleBase:RU000414}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC         Evidence={ECO:0000256|RuleBase:RU000414};
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase family.
CC       {ECO:0000256|ARBA:ARBA00008714, ECO:0000256|RuleBase:RU000414}.
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DR   EMBL; CP000151; ABB09468.1; -; Genomic_DNA.
DR   EMBL; CP024943; AYQ39381.1; -; Genomic_DNA.
DR   EMBL; WNDV01000039; KAF1032284.1; -; Genomic_DNA.
DR   EMBL; LDWP01000092; KML35678.1; -; Genomic_DNA.
DR   EMBL; CABVPZ010000008; VWB40519.1; -; Genomic_DNA.
DR   EMBL; CABVQE010000032; VWC06055.1; -; Genomic_DNA.
DR   EMBL; CABVPW010000036; VWC24525.1; -; Genomic_DNA.
DR   EMBL; CABVPY010000119; VWC50051.1; -; Genomic_DNA.
DR   EMBL; CABVQI010000007; VWC83266.1; -; Genomic_DNA.
DR   EMBL; CABVQP010000009; VWD08454.1; -; Genomic_DNA.
DR   EMBL; CABVQK010000014; VWD30104.1; -; Genomic_DNA.
DR   EMBL; CABVQN010000075; VWD63933.1; -; Genomic_DNA.
DR   EMBL; CABWIJ010000014; VWM15041.1; -; Genomic_DNA.
DR   RefSeq; WP_011352986.1; NZ_WNDV01000039.1.
DR   GeneID; 84793771; -.
DR   KEGG; bur:Bcep18194_A5874; -.
DR   PATRIC; fig|482957.22.peg.2865; -.
DR   HOGENOM; CLU_031625_0_0_4; -.
DR   Proteomes; UP000002705; Chromosome 1.
DR   Proteomes; UP000036521; Unassembled WGS sequence.
DR   Proteomes; UP000280305; Chromosome 1.
DR   Proteomes; UP000467522; Unassembled WGS sequence.
DR   Proteomes; UP000494110; Unassembled WGS sequence.
DR   Proteomes; UP000494126; Unassembled WGS sequence.
DR   Proteomes; UP000494129; Unassembled WGS sequence.
DR   Proteomes; UP000494169; Unassembled WGS sequence.
DR   Proteomes; UP000494170; Unassembled WGS sequence.
DR   Proteomes; UP000494177; Unassembled WGS sequence.
DR   Proteomes; UP000494218; Unassembled WGS sequence.
DR   Proteomes; UP000494250; Unassembled WGS sequence.
DR   Proteomes; UP000494274; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.287.990; Fe,Mn superoxide dismutase (SOD) domain; 1.
DR   Gene3D; 3.55.40.20; Iron/manganese superoxide dismutase, C-terminal domain; 1.
DR   InterPro; IPR001189; Mn/Fe_SOD.
DR   InterPro; IPR019833; Mn/Fe_SOD_BS.
DR   InterPro; IPR019832; Mn/Fe_SOD_C.
DR   InterPro; IPR019831; Mn/Fe_SOD_N.
DR   InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR   InterPro; IPR036314; SOD_C_sf.
DR   PANTHER; PTHR42769; SUPEROXIDE DISMUTASE; 1.
DR   PANTHER; PTHR42769:SF3; SUPEROXIDE DISMUTASE [FE] 2, CHLOROPLASTIC; 1.
DR   Pfam; PF02777; Sod_Fe_C; 1.
DR   Pfam; PF00081; Sod_Fe_N; 1.
DR   PIRSF; PIRSF000349; SODismutase; 1.
DR   PRINTS; PR01703; MNSODISMTASE.
DR   SUPFAM; SSF54719; Fe,Mn superoxide dismutase (SOD), C-terminal domain; 1.
DR   SUPFAM; SSF46609; Fe,Mn superoxide dismutase (SOD), N-terminal domain; 1.
DR   PROSITE; PS00088; SOD_MN; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|PIRSR:PIRSR000349-1};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU000414}.
FT   DOMAIN          3..82
FT                   /note="Manganese/iron superoxide dismutase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00081"
FT   DOMAIN          89..189
FT                   /note="Manganese/iron superoxide dismutase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02777"
FT   BINDING         27
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000349-1"
FT   BINDING         74
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000349-1"
FT   BINDING         157
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000349-1"
FT   BINDING         161
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000349-1"
SQ   SEQUENCE   192 AA;  21103 MW;  4E7BBFFB73D72BBC CRC64;
     MAHTLPPLPY AEDALAPTIS LETIQYHYGK HHQAYVTNLN NLIPGTEFEN LSLEEIVKKS
     SGGIFNNAAQ IWNHTFFWNS LSPNGGGAPT GALGDAINAK WGSYDAFKEA FTKAAVGTFG
     SGWAWLVKKA DGSLDIVSTS NAATPLTTAD KALLTIDVWE HAYYIDYRNA RPKFVEAFWN
     IVNWDFAAKN FA
//