Reviewed, UniProtKB/Swiss-Prot Q39827 (SPE1_SOYBN)

Names and origin

Protein names	Recommended name:     Arginine decarboxylase       Short name=ARGDC       Short name=ADC     EC=4.1.1.19
Organism	Glycine max (Soybean)
Taxonomic identifier	3847 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids I › Fabales › Fabaceae › Papilionoideae › Phaseoleae › Glycine

Protein attributes

Sequence length	692 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2.
Cofactor	Pyridoxal phosphate. Magnesium.
Pathway	Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.
Sequence similarities	Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Ontologies

Keywords
Biological process	Putrescine biosynthesis Spermidine biosynthesis
Ligand	Magnesium Pyridoxal phosphate
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro putrescine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW spermidine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 692	692	Arginine decarboxylase		PRO_0000149954
Regions
	Region	337 – 347	11	Substrate-binding By similarity
Amino acid modifications
	Modified residue	153	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q39827-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 31BA9C207B5A6EF3	FASTA	692	74,595
	10 20 30 40 50 60 MPVLACCVDA AAPPGYAFAG DISFPAPIAF TGVPPATADD TNNSNNHWSP SLSAALYNVD 70 80 90 100 110 120 GWGGPYFAVN TAGNISVRPH GSDTVSHQEI DLLKIVKKAS DPKSLGGLSL QLPLIARFPD 130 140 150 160 170 180 VLKNRLESLQ SAFDYAIQSG GYESHYQGVY PVKCNQDRFV VEDIVKFGSP FRFGLEAGSK 190 200 210 220 230 240 PELLLAMSCL CKGNPDGLLI CNGFKDAEYI SLALVANKLA LNTVIVVEQE EEVDLIVELS 250 260 270 280 290 300 KKLCIKPVIG LRAKLRTKHS GHFGGIFRRR GKFGLTTARV LRVVKNLDLA GMLDCLQLLH 310 320 330 340 350 360 FHIGSQIPST ALLADGVGEA AQIYCELVRL GANMRVIDIG GGLGIDYDGS KSCDSDISVE 370 380 390 400 410 420 YGLEEYAAAV VHAVQCVCDR SVKHPVICSE SGRAIVSHHS VLIFEAVGTS STNGGGAPPA 430 440 450 460 470 480 LSAHYLAEEL SEDYGYLSEL AFRGDYETCL VYTEEMKERC VEQFKQGTVC MEQLAAVEGL 490 500 510 520 530 540 CELVRKAVGA AESVRRYHVN LSIFTSVPDA WGIEQVFPII PIHRLDEKPS VRGILSDLTC 550 560 570 580 590 600 DSDGKIDKFI NGESSLPLHE MEGGRTYYLG MFLGGAYEEA LGGVHNLFGG PSVVRVSQSD 610 620 630 640 650 660 GPHSFAVTRA VPGPSCGDVL RVMQHQPELM FETLKHRAQE YVSHDNAAAL LAAGLARTFD 670 680 690 RMPYLLSLSS FVADDVAAAV PAAQDLGEQW SY

References

[1]	"A cDNA encoding an arginine decarboxylase from soybean hypocotyls." Nam K.H., Lee S.H., Lee J.H. Plant Gene Register PGR95-142 Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	U35367 mRNA. Translation: AAD09204.1.
PIR	T06593.
UniGene	Gma.18066
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	4.1.1.19. 299.
Gene expression databases
Genevestigator	Q39827.
Family and domain databases
InterPro	IPR002985. Arg_decrbxlase. IPR000183. De-COase2. [Graphical view]
PANTHER	PTHR11482:SF3. Arg_decrbxlase. 1 hit.
Pfam	PF02784. Orn_Arg_deC_N. 1 hit. PF00278. Orn_DAP_Arg_deC. 1 hit. [Graphical view]
PIRSF	PIRSF001336. Arg_decrbxlase. 1 hit.
PRINTS	PR01180. ARGDCRBXLASE. PR01179. ODADCRBXLASE.
TIGRFAMs	TIGR01273. speA. 1 hit.
PROSITE	PS00878. ODR_DC_2_1. 1 hit. PS00879. ODR_DC_2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SPE1_SOYBN

Accession

Primary (citable) accession number: Q39827

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	November 1, 1996
Last modified:	October 13, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)