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Protein
Submitted name:

Polyketide reductase

Gene

PKR

Organism
Glycyrrhiza echinata (Licorice)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei63 – 631Proton donorUniRule annotation
Sitei92 – 921Lowers pKa of active site TyrUniRule annotation
Binding sitei125 – 1251SubstrateUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Polyketide reductaseImported
Gene namesi
Name:PKRImported
OrganismiGlycyrrhiza echinata (Licorice)Imported
Taxonomic identifieri46348 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeGalegeaeGlycyrrhiza

Structurei

3D structure databases

ProteinModelPortaliQ39774.
SMRiQ39774. Positions 10-317.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini34 – 297264Aldo_ket_redInterPro annotationAdd
BLAST

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 2 hits.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q39774-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAAAAAIE IPTKVLPNST CELRVPVIGM GSAPDFTCKK DTKEAIIEAI
60 70 80 90 100
KQGYRHFDTA AAYGSETALG EALKEARDLG LVTREELFVT SKLWVTENHP
110 120 130 140 150
HLVIPALRKS LETLQLEYLD LYLIHWPLSS QPGKFSFPIQ VEDLLPFDVK
160 170 180 190 200
GVWESMEECL KLGLTKAIGV SNFSVKKLQN LLSVATIRPA VNQVEMNLAW
210 220 230 240 250
QQKKLREFCT ANGIVLTAFS PLRKGASRGP NEVMENDMLK GIAEAHGKSI
260 270 280 290 300
AQVSLRWLYE QGVTFVAKSY DKERMNQNLQ IFDWELTTED HQKIDQIKQN
310
RLIPGPTKPQ LNDLWDDEL
Length:319
Mass (Da):35,774
Last modified:November 1, 1996 - v1
Checksum:iB9DAE8237CF8220C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83718 mRNA. Translation: BAA12084.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83718 mRNA. Translation: BAA12084.1.

3D structure databases

ProteinModelPortaliQ39774.
SMRiQ39774. Positions 10-317.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 2 hits.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ39774_GLYEC
AccessioniPrimary (citable) accession number: Q39774
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.