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Q396Y9 (UXUA_BURS3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannonate dehydratase
EC=4.2.1.8
Alternative name(s):
D-mannonate hydrolase
Gene names
Name:uxuA
Ordered Locus Names:Bcep18194_B1358
OrganismBurkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) [Complete proteome] [HAMAP]
Taxonomic identifier269483 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106

Sequence similarities

Belongs to the mannonate dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 352352Mannonate dehydratase HAMAP MF_00106
PRO_0000231052

Sequences

Sequence LengthMass (Da)Tools
Q396Y9 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: E99111E9A8A7BDFF

FASTA35238,955
        10         20         30         40         50         60 
MSFRWYGESD PVSLQYIRQI PGVTHIVSAI YDEPVGEVWP AHKIDALKAT IERAGLQFEV 

        70         80         90        100        110        120 
VESVPVHEDI KLGKPGRDRL IDHYRQTIRH LGAAGVRVIC YNFMPVFDWT RTELSKTLDD 

       130        140        150        160        170        180 
GSTCLAFSTD AVDRIDPDDG IALPGWDSSY QPEQLKALLA EYRDVDEAAL WANLEYFLKA 

       190        200        210        220        230        240 
IIPVAEEAGV KMAIHPDDPP RPIFGLPRIV KNRDDLARIV RIVDTPANGL TLCSGSLGAG 

       250        260        270        280        290        300 
PQNDVEALVR EFGAMGRIHF AHIRNVKVDA NGDFEETAHL SSCGSLDIAA IVKAYHDTGF 

       310        320        330        340        350 
TGYVRPDHGR MIWGETGKPG YGLYDRALGA VYLNGLWEAL AKFDRTPSLA TQ

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia sp. 383."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 383.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000152 Genomic DNA. Translation: ABB11472.1.
RefSeqYP_372116.1. NC_007511.1.

3D structure databases

ProteinModelPortalQ396Y9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ396Y9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3753123.
GenomeReviewsGene locus Bcep18194_B1358 in contig CP000152_GR.
KEGGbur:Bcep18194_B1358.
NMPDRfig|269483.3.peg.1277.
PATRIC19293501. VBIBurSp120713_6113.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1312.
HOGENOMHBG585927.
OMADIKLGKP.
ProtClustDBPRK03906.

Enzyme and pathway databases

BioCycBSP36773:BCEP18194_B1358-MONOMER.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXUA_BURS3
AccessionPrimary (citable) accession number: Q396Y9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: November 22, 2005
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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